Structure
PptT inhibitor 8918 Biochemical
PptT inhibitor 8918
Purity
>98% (HPLC)
Synonyms
PptT inhibitor 8918; Compound 8918; PptT inhibitor 8918 biochemical
Purity/Purification
>98% (HPLC)
Target
Antibacterial
Receptor
Antibacterial
Chemical Name
Amidino-urea 1-[(2, 6-diethylphenyl)-3-N-ethylcarbamimodoyl]urea
Molecular Formula
C14H22N4O
CAS Number
65009-19-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for PptT inhibitor 8918 biochemical
PptT inhibitor 8918 (Compound 8918) is a mycobactericidal amidino-urea compound that targets phosphopantetheinyl transferase (PptT, IC50=2.5uM), shows an MIC90 of 3.1uM against Mtb H37Rv; also exhibits MIC90s ranged from 0.56-3.0uM (median 1.5uM) against 29 clinical isolates of Mtb; inhibits growth of WT Mtb, but not of the pptT mutant W170S or WT Mtb expressing the pptT W170S mutant; kills Mycobacterium tuberculosis (Mtb) by binding and partially inhibiting PptT.
Product Categories/Family for PptT inhibitor 8918 biochemical
References
1. Ballinger E, et al. Science. 2019 Feb 1; 363 (6426). pii: eaau8959. doi: 10.1126/science.aau8959.
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Product Notes
The PptT inhibitor 8918 (Catalog #AAA3605467) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PptT inhibitor 8918, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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