Structure
D715-2441 Biochemical
D715-2441
Purity
>98% (HPLC)
Synonyms
D715-2441; D 715-2441; D715-2441 biochemical
Purity/Purification
>98% (HPLC)
Target
Influenza Virus
Receptor
Influenza Virus
Chemical Name
1, 3-dihydroxy-6H-benzo[c]chromen-6-one
SMILES
C1=CC=C2C(=C1)C3=C(C=C(C=C3OC2=O)O)O
Molecular Formula
C13H8O4
CAS Number
54245-10-2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for D715-2441 biochemical
D715-2441 (D 715-2441) is a novel antiviral compound that interferes with the conserved cap-binding domain of the PB2 protein, exhibits potent antiviral activity against influenza A viruses (IAVs) with IC50 of 1.7-4.4uM; does not inhibit both viral entry and release, disrupts early influenza A virus replication, reduces vRNP activity and affects PB2 protein localization; shows binding affinity to influenza PB2cap protein with Kd of 0.118uM; demonstrates a remarkable synergistic antiviral effect (FICI value of 0.40) combined with zanamivir.
Product Categories/Family for D715-2441 biochemical
References
1. Liu T, et al. Mol Pharm. 2018 Aug 23. doi: 10.1021/acs.molpharmaceut.8b00531.
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Product Notes
The D715-2441 (Catalog #AAA3604941) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "D715-2441, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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