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Structure

TMS, Inhibitor

TMS

Purity
>98% (HPLC)
Synonyms
TMS; 2; 3; 4; 5-Tetramethoxystilbene; inhibitor
Ordering
 
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For Research Use Only!
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 10mM
Target
P450
Receptor
CYP450 1B1
Chemical Name
(E)-1-(3, 5-dimethoxystyryl)-2, 4-dimethoxybenzene
SMILES
COC1=CC(OC)=CC(/C=C/C2=CC=C(OC)C=C2OC)=C1
Molecular Formula
C18H20O4
CAS Number
24144-92-1
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Related Product Information for TMS, inhibitor
TMS is a very selective and potent competitive inhibitor of P450 1B1 (CYP1A1). It has strong selectivity among P450 family 1 enzymes. TMS exhibits 50-fold selectivity for P450 1B1 over P4501A1 and 500-fold selectivity for P450 1B1 over P450 1A2.
Product Categories/Family for TMS, inhibitor
References
1. Einem Lindeman T, et al. The resveratrol analogue, 2, 3', 4, 5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzoapyrene-Dna adduct formation in MCF-7 cells exposed to benzoapyrene. Mutagenesis. 2011 Sep; 26 (5):629-35.

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Product Notes

The TMS (Catalog #AAA3603694) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TMS, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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