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Structure

BMP signaling agonist sb4 Biochemical

BMP signaling agonist sb4

Purity
>98% (HPLC)
Synonyms
BMP signaling agonist sb4; SB 4; SB4; SB-4; BMP signaling agonist sb4 biochemical
Ordering
For Research Use Only!
Purity/Purification
>98% (HPLC)
Target
TGFBR
Receptor
TGFBR
Chemical Name
2-((4-bromobenzyl)thio)benzo[d]oxazole
SMILES
BrC1=CC=C(CSC2=NC3=CC=CC=C3O2)C=C1
Molecular Formula
C14H10BrNOS
CAS Number
100874-08-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Structure
Related Product Information for BMP signaling agonist sb4 biochemical
BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes; increases the phosphorylation of key second messengers (SMADs-1/5/9) and also increased expression of direct target genes (inhibitors of DNA binding, ID1 and ID3) in canonical BMP signaling.
Product Categories/Family for BMP signaling agonist sb4 biochemical
References
1. Bradford STJ, et al. J Biol Chem. 2019 Jan 2. pii: jbc.RA118.006817.

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Product Notes

The BMP signaling agonist sb4 (Catalog #AAA3600057) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BMP signaling agonist sb4, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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