Western Blot (WB)
Rabbit anti-Human, mouse CD79 alpha Polyclonal Antibody | anti-CD79 alpha antibody
Anti-CD79alpha antibody
Reactivity
Human, mouse
Applications
Western Blot, Immunocytochemistry
Purity
Immunogen affinity purified
Synonyms
CD79 alpha; Polyclonal Antibody; Anti-CD79alpha antibody; Polyclonal Anti- CD79alpha; Polyclonal Anti- CD79a; anti-CD79 alpha antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified
Form/Format
Liquid
Applicable Applications for anti-CD79 alpha antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
WB (1:1000-2000); ICC (1:50-100)
Immunogen
A synthetic peptide (conjugated to KLH) corresponding to the region of CD79α.
Storage Buffer
In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide
Preparation and Storage
Store at 4°C after thawing (1 week). Aliquot and store at -20° C for long term (at least one year). Avoid repeated freeze and thaw cycles
Western Blot (WB)
Western Blot (WB)
Testing Data
Testing Data
Related Product Information for anti-CD79 alpha antibody
CD79a molecule, immunoglobulin-associated alpha, also known as mb-1, is expressed in B lymphocytes and is part of the B-cell antigen receptor complex.[1] This complex consists of a clonally restricted antigen-binding molecule (membrane Ig) associated noncovalently with an 'invariant' transducer/transporter complex. It is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. [2] It is interacts with and increases activity of some Src-family tyrosine kinases. And also represses BCR signaling during development of immature B-cells. [3]
References
1. Ha, H., Kubagawa, H., Burrows, P. D. Molecular cloning and expression pattern of a human gene homologous to the murine mb-1 gene. J. Immun. 148: 1526-1531, 1992. 2. Luisiri P., Lee Y.J., Eisfelder B.J., Clark M.R. "Cooperativity and segregation of function within the Ig-alpha/beta heterodimer of the B cell antigen receptor complex." J. Biol. Chem. 271:5158-5163(1996) 3. Tseng J., Eisfelder B.J., Clark M.R. "B-cell antigen receptor-induced apoptosis requires both Ig alpha and Ig beta." Blood 89:1513-1520(1997)
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Product Notes
The CD79 alpha (Catalog #AAA355200) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD79alpha antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD79 alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). WB (1:1000-2000); ICC (1:50-100). Researchers should empirically determine the suitability of the CD79 alpha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD79 alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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