KIF1A blocking peptide
KIF1A Peptide - N-terminal region
Target Description: KIF1A is the motor for anterograde axonal transport of synaptic vesicle precursors.The protein encoded by this gene is a member of the kinesin family. This protein is highly similar to mouse heavy chain kinesin member 1A protein which is an anterograde motor protein that transports membranous organelles along axonal microtubules. It is thought that this protein may play a critical role in the development of axonal neuropathies resulting from impaired axonal transport. There are multiple polyadenylation sites found in this gene. Sequence Note: X90840.1 is a chimeric sequence. Only the ATSV region was propagated into this RefSeq record. [6/26/03, RefSeq staff]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Uniprot Description
KIF1A: a member of the kinesin motor protein family. Motor for anterograde axonal transport of synaptic vesicle precursors. Interacts with PPFIA1 and PPFIA4. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Microtubule-binding
Chromosomal Location of Human Ortholog: 2q37.3
Cellular Component: kinesin complex; microtubule; neuron projection; cell soma; cytoplasm
Molecular Function: plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; motor activity; ATP binding
Biological Process: vesicle-mediated transport; metabolic process; cytoskeleton-dependent intracellular transport; anterograde axon cargo transport; microtubule-based movement
Disease: Neuropathy, Hereditary Sensory, Type Iic; Spastic Paraplegia 30, Autosomal Recessive; Neuropathy, Hereditary Sensory And Autonomic, Type Iia; Mental Retardation, Autosomal Dominant 9
Research Articles on KIF1A
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Product Notes
The KIF1A kif1a (Catalog #AAA3226781) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's KIF1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the KIF1A kif1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIF1A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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