SRP72 blocking peptide
SRP72 Peptide - middle region
Gene Names
SRP72; BMFF; BMFS1; HEL103
Applications
Western Blot
Synonyms
SRP72; SRP72 Peptide - middle region; SRP72 blocking peptide
Form/Format
Lyophilized powder
Sequence Length
671
Applicable Applications for SRP72 blocking peptide
Western Blot (WB)
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Related Product Information for SRP72 blocking peptide
This is a synthetic peptide designed for use in combination with anti-SRP72 antibody made
Target Description: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP72 binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
Target Description: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP72 binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
Product Categories/Family for SRP72 blocking peptide
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
74kDa
NCBI Official Full Name
signal recognition particle subunit SRP72 isoform 1
NCBI Official Synonym Full Names
signal recognition particle 72
NCBI Official Symbol
SRP72
NCBI Official Synonym Symbols
BMFF; BMFS1; HEL103
NCBI Protein Information
signal recognition particle subunit SRP72
UniProt Protein Name
Signal recognition particle subunit SRP72
Protein Family
UniProt Gene Name
SRP72
UniProt Synonym Gene Names
SRP72
UniProt Entry Name
SRP72_HUMAN
NCBI Description
This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
