Western Blot (WB)
(Host: RabbitTarget Name: Oprm1Sample Type: Mouse Brain lysatesAntibody Dilution: 1.0ug/ml)
Rabbit Oprm1 Polyclonal Antibody | anti-OPRM1 antibody
Oprm1 Antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: Oprm1Sample Type: Mouse Brain lysatesAntibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: Oprm1Sample Type: Mouse Brain lysatesAntibody Dilution: 1.0ug/ml)
Target Description: This gene encodes the mu opioid receptor which is where drugs such as morphine and other opioids have pharmacological effects. Alternatively spliced transcript variants have been found for this gene, however, many of these variants may be NMD candidates.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the mu opioid receptor which is where drugs such as morphine and other opioids have pharmacological effects. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Uniprot Description
MOR-1: a Gi-protein-coupled receptor for beta-endorphin, morphine and other opiates. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Ligand-binding inactivates adenylyl cyclase, and activates a variety of G-beta-gamma-dependent pathways including the MAPK and the PI3K/Akt cascades. Two splice-variant isoforms have been described.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR
Cellular Component: dendrite cytoplasm; neuron projection; focal adhesion; integral to plasma membrane; dendrite; integral to membrane; perikaryon; cytosol; lipid raft; membrane; cytoplasm; plasma membrane; sarcolemma
Molecular Function: voltage-gated calcium channel activity; G-protein coupled receptor activity; protein domain specific binding; neuropeptide binding; signal transducer activity; protein binding; opioid receptor activity; G-protein alpha-subunit binding; G-protein beta-subunit binding; beta-endorphin receptor activity; filamin binding
Biological Process: positive regulation of neurogenesis; positive regulation of nitric oxide biosynthetic process; cellular response to stress; negative regulation of nitric oxide biosynthetic process; negative regulation of adenylate cyclase activity; locomotory behavior; behavioral response to ethanol; signal transduction; sensory perception of pain; synaptic transmission; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; response to ethanol; neuropeptide signaling pathway; positive regulation of appetite; reduction of cytosolic calcium ion concentration; opioid receptor, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); regulation of sensory perception of pain; G-protein signaling, adenylate cyclase inhibiting pathway; regulation of excitatory postsynaptic membrane potential; dopamine receptor, adenylate cyclase activating pathway
Research Articles on OPRM1
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Product Notes
The OPRM1 oprm1 (Catalog #AAA3216417) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Oprm1 Antibody - middle region reacts with Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's Oprm1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the OPRM1 oprm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: CYGLMILRLK SVRMLSGSKE KDRNLRRITR MVLVVVAVFI VCWTPIHIYV. It is sometimes possible for the material contained within the vial of "Oprm1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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