Western Blot (WB)
(WB Suggested Anti-RCAN2 Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate)
Rabbit RCAN2 Polyclonal Antibody | anti-RCAN2 antibody
RCAN2 antibody - middle region
Western Blot (WB)
(WB Suggested Anti-RCAN2 Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate)
Western Blot (WB)
(WB Suggested Anti-RCAN2 Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate)
Target Description: RCAN2 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. RCAN2 could play a role during central nervous system development.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
RCAN2: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. Belongs to the RCAN family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 6p12.3
Molecular Function: nucleotide binding
Biological Process: calcineurin-NFAT signaling pathway; short-term memory; response to oxidative stress; locomotion during locomotory behavior
Research Articles on RCAN2
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Product Notes
The RCAN2 rcan2 (Catalog #AAA3210612) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RCAN2 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RCAN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the RCAN2 rcan2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LHETQFRGKK LKLYFAQVQT PETDGDKLHL APPQPAKQFL ISPPSSPPVG. It is sometimes possible for the material contained within the vial of "RCAN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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