Western Blot (WB)
(WB Suggested Anti-TIPIN Antibody Titration: 0.2-1 ug/mlPositive Control: Human heart)
Rabbit TIPIN Polyclonal Antibody | anti-TIPIN antibody
TIPIN antibody - middle region
Western Blot (WB)
(WB Suggested Anti-TIPIN Antibody Titration: 0.2-1 ug/mlPositive Control: Human heart)
Western Blot (WB)
(WB Suggested Anti-TIPIN Antibody Titration: 0.2-1 ug/mlPositive Control: Human heart)
Target Description: TIPIN belongs to the CSM3 family. TIPIN is required for normal progression of S-phase. It is important for cell survival after DNA damage or replication stress. TIPIN may be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is part of the replisome complex, a group of proteins that support DNA replication. It binds TIM, which is involved in circadian rhythm regulation, and aids in protecting cells against DNA damage and stress. Two pseudogenes and two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Uniprot Description
TIPIN: Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Belongs to the CSM3 family.
Chromosomal Location of Human Ortholog: 15q22.31
Cellular Component: nucleoplasm; Golgi apparatus; intracellular membrane-bound organelle; nuclear chromatin; cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: mitosis; intra-S DNA damage checkpoint; cell division; positive regulation of cell proliferation; replication fork protection; DNA replication checkpoint; regulation of DNA replication during S phase; response to UV
Research Articles on TIPIN
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Product Notes
The TIPIN tipin (Catalog #AAA3210015) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TIPIN antibody - middle region reacts with Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TIPIN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the TIPIN tipin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: SESEMFASEL SRSLTEEQQQ RIERNKQLAL ERRQAKLLSN SQTLGNDMLM. It is sometimes possible for the material contained within the vial of "TIPIN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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