Western Blot (WB)
(Host: RabbitTarget Name: RNF125Sample Tissue: Human HT1080 Whole CellAntibody Dilution: 1ug/ml)
Rabbit RNF125 Polyclonal Antibody | anti-RNF125 antibody
RNF125 antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: RNF125Sample Tissue: Human HT1080 Whole CellAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: RNF125Sample Tissue: Human HT1080 Whole CellAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: RNF125Sample Tissue: Human THP-1 Whole CellAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: RNF125Sample Tissue: Human THP-1 Whole CellAntibody Dilution: 1ug/ml)
Western Blot (WB)
(WB Suggested Anti-RNF125 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: THP-1 cell lysate)
Western Blot (WB)
(WB Suggested Anti-RNF125 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: THP-1 cell lysate)
Target Description: This gene encodes a novel E3 ubiquitin ligase that contains an N-terminal RING finger domain. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012]
Uniprot Description
RNF125: E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins.
Protein type: Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.19; EC 6.3.2.-; Ligase
Chromosomal Location of Human Ortholog: 18q12.1
Molecular Function: zinc ion binding; ubiquitin-protein ligase activity; ligase activity
Biological Process: protein ubiquitination; innate immune response; negative regulation of interferon type I production
Disease: Tenorio Syndrome
Research Articles on RNF125
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Product Notes
The RNF125 rnf125 (Catalog #AAA3206775) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RNF125 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RNF125 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the RNF125 rnf125 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: ENPSSFSGSL IRHLQVSHTL FYDDFIDFNI IEEALIRRVL DRSLLEYVNH. It is sometimes possible for the material contained within the vial of "RNF125, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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