Rabbit anti-Mouse phospho-Ron Polyclonal Antibody | anti-Ron antibody
phospho-Ron (Ser1349) Polyclonal Antibody
Gene Names
Mst1r; Fv2; Ron; STK; Fv-2; PTK8; CD136; CDw136
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Purity
affinity purified by Protein A
Synonyms
phospho-Ron; Polyclonal Antibody; phospho-Ron (Ser1349) Polyclonal Antibody; MST1R(phospho S1349); c met related tyrosine kinase; CD136; CD136 antigen; CDw136; Macrophage stimulating 1 receptor (c met related tyrosine kinase); Macrophage stimulating 1 receptor; Macrophage stimulating protein receptor alpha chain; MACROPHAGE STIMULATING PROTEIN RECEPTOR; Macrophage stimulating protein receptor beta chain; Macrophage-Stimulating 1 Receptor (MST1R); Macrophage-stimulating protein receptor beta chain; MSP receptor; Mst1r; MST1R variant RON30; MST1R variant RON62; p185 RON; p185-Ron; Protein-tyrosine kinase 8; PTK 8; ptk8; PTK8 protein tyrosine kinase 8; Recepteur d'origine nantais (RON); RON; RON protein tyrosine kinase; RON variant E2E3; RON_MOUSE; Soluble RON variant 1; Soluble RON variant 2; Soluble RON variant 3; Soluble RON variant 4; Stem cell derived tyrosine kinase; anti-Ron antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Specificity
phospho-Ron (Ser1349) Polyclonal Antibody detects endogenous levels of Ron protein only when phosphorylated at Ser1349.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-Ron antibody
Flow Cytometry (FC/FACS/FCM)
Application Notes
FC/FACS/FCM: 3ug/Test
Immunogen
KLH conjugated Synthesised phosphopeptide derived from mouse MST1R around the phosphorylation site of Ser1349:DG(p-S)VP
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Related Product Information for anti-Ron antibody
MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers. Ron expression has been documented in many normal human tissues. ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uterus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
150,519 Da
NCBI Official Full Name
macrophage-stimulating protein receptor isoform 1
NCBI Official Synonym Full Names
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
NCBI Official Symbol
Mst1r
NCBI Official Synonym Symbols
Fv2; Ron; STK; Fv-2; PTK8; CD136; CDw136
NCBI Protein Information
macrophage-stimulating protein receptor; p185-Ron; MSP receptor; friend virus susceptibility 2; stem cell-derived tyrosine kinase; receptor protein tyrosine kinase, c-met-related
UniProt Protein Name
Macrophage-stimulating protein receptor
UniProt Gene Name
Mst1r
UniProt Synonym Gene Names
Ron; Stk; MSP receptor
UniProt Entry Name
RON_MOUSE
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Product Notes
The Ron mst1r (Catalog #AAA3015449) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The phospho-Ron (Ser1349) Polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's phospho-Ron can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). FC/FACS/FCM: 3ug/Test. Researchers should empirically determine the suitability of the Ron mst1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "phospho-Ron, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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