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Bcl-7a blocking peptide

Bcl-7a (N62) Peptide

Applications
Blocking
Purity
Synthetic peptide Bcl-7a (N62). (Note: the amino acid sequence is proprietary).
The purity is >98%.
Synonyms
Bcl-7a; Bcl-7a (N62) Peptide; B cell CLL/lymphoma 7; B cell CLL/lymphoma 7 protein family member A; B cell CLL/lymphoma 7A; B-cell CLL/lymphoma 7 protein family member A; BCL 7; BCL7; bcl7a; BCL7A; Bcl-7a blocking peptide
Ordering
For Research Use Only!
Specificity
This peptide can be used with studies using MBS3013898 Bcl-7a (N62) pAb.
Purity/Purification
Synthetic peptide Bcl-7a (N62). (Note: the amino acid sequence is proprietary).
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
210
Applicable Applications for Bcl-7a blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for Bcl-7a blocking peptide
Bcl-7a (B-cell CLL/lymphoma 7 protein family member A) is a 210 amino acid protein that belongs to the Bcl-7 family. Chromosomal aberrations involving a disruption of the amino-terminus of Bcl-7a may be a cause of B-cell nonHodgkin lymphoma (BNHL). Bcl-7b and Bcl-7c proteins share 90% identity with the N-terminal 51 amino acids of Bcl-7a, suggesting that the three genes are members of an evolutionarily conserved gene family. Bcl-7 gene family may be involved in early development. The Bcl-7a protein interacts with a novel human Polycomb ring finger gene and exists as two alternatively spliced isoforms. Bcl-7a may play a role in GC reaction and/or B-cell lymphomagenesis. The Bcl-7a gene maps to human chromosome 12q24.31. Chromosome 12 encodes over 1, 100 genes and comprises approximately 4.5% of the human genome.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
B-cell CLL/lymphoma 7 protein family member A isoform b
UniProt Protein Name
B-cell CLL/lymphoma 7 protein family member A
UniProt Gene Name
BCL7A
UniProt Entry Name
BCL7A_HUMAN

Uniprot Description

Bcl-7A: Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions. Belongs to the BCL7 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding

Chromosomal Location of Human Ortholog: 12q24.13

Biological Process: negative regulation of transcription, DNA-dependent

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Product Notes

The Bcl-7a bcl7a (Catalog #AAA3013899) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Bcl-7a can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the Bcl-7a bcl7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bcl-7a, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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