Rabbit anti-Human USP10 Polyclonal Antibody | anti-USP10 antibody

USP10 Polyclonal Antibody

Cat. Num. AAA3013643

• Gene Names: USP10; UBPO
• Reactivity: Human
• Applications: Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
• Purity: ProA affinity purified
• Synonyms: USP10; Polyclonal Antibody; USP10 Polyclonal Antibody; KIAA0190; Deubiquitinating enzyme 10; MGC124997; MGC2621; Ubiquitin carboxyl terminal hydrolase 10; Ubiquitin carboxyl-terminal hydrolase 10; Ubiquitin specific peptidase 10; Ubiquitin specific processing protease 10; Ubiquitin specific protease 10; Ubiquitin thioesterase 10; Ubiquitin thiolesterase 10; Ubiquitin-specific-processing protease 10; UBP10; UBPO; USP 10; anti-USP10 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: USP10 polyclonal antibody detects endogenous levels of USP10 protein.
• Purity/Purification: ProA affinity purified
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 802

• Applicable Applications for anti-USP10 antibody: Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Application Notes: WB: 1:500-1:2,000; ICC: 1:50-1:200; IHC: 1:50-1:200
• Immunogen: Recombinant protein
• Preparation and Storage: Store at 4 degree C after thawing.; Aliquot store at -20 degree C or -80 degree C.; Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of USP10 on SiHa (1) and A549 (2) cell lysate using anti-USP10 antibody at 1/500 dilution.)

Immunocytochemistry (ICC)

(ICC staining USP10 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Related Product Information for anti-USP10 antibody

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP10 (ubiquitin specific peptidase 10), also known as UBPO, is a 798 amino acid protein that belongs to the ubiquitin-specific protease family of cysteine proteases. Expressed in a variety of tissues, USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates, possibly playing a role in the activity of the DNA-bound androgen receptor complex.

NCBI and Uniprot Product Information

• NCBI GI #: 440918695
• NCBI GeneID: 9100
• NCBI Accession #: NP_001259004.1
• NCBI GenBank Nucleotide #: NP_001259004.1
• UniProt Accession #: Q14694
• Molecular Weight: 110kDa
• NCBI Official Full Name: ubiquitin carboxyl-terminal hydrolase 10 isoform 1
• NCBI Official Synonym Full Names: ubiquitin specific peptidase 10
• NCBI Official Symbol: USP10
• NCBI Official Synonym Symbols: UBPO
• NCBI Protein Information: ubiquitin carboxyl-terminal hydrolase 10
• UniProt Protein Name: Ubiquitin carboxyl-terminal hydrolase 10
• UniProt Gene Name: USP10
• UniProt Synonym Gene Names: KIAA0190
• UniProt Entry Name: UBP10_HUMAN

NCBI Description

Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013]