Western blot: 1:5,000 to 1:50,000 dilution.
Indirect ELISA: 1: 200,000 to 1:400,000 dilution for wells coated with 800ng/well antigen.
Immune-depletion: The antibody can be used for fibrinogen removal from human blood sample using affinity method.
NCBI and Uniprot Product Information
Uniprot Description
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
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Product Notes
The FGG fgg (Catalog #AAA592295) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Fibrinogen reacts with Human, others not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's Fibrinogen can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Indirect ELISA, Immune-depletion. Suggested application and antibody working condition: Western blot: 1:5,000 to 1:50,000 dilution. Indirect ELISA: 1: 200,000 to 1:400,000 dilution for wells coated with 800ng/well antigen. Immune-depletion: The antibody can be used for fibrinogen removal from human blood sample using affinity method. Researchers should empirically determine the suitability of the FGG fgg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fibrinogen, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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