Western Blot (WB)
(Western Blot (WB) analysis of ZFYVE19 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysate (40ug) Lane2:MCF-7 whole cell lysate (40ug) Lane3:HEK293T whole cell lysate (40ug) Lane4:L02 whole cell lysate (20ug))
Rabbit anti-Human ZFYVE19 Polyclonal Antibody | anti-ZFYVE19 antibody
ZFYVE19 Polyclonal Antibody
Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
ZFYVE19; Polyclonal Antibody; ZFYVE19 Polyclonal Antibody; Abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; Zinc finger FYVE domain-containing protein 19; MPFYVE; anti-ZFYVE19 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
ZFYVE19 polyclonal antibody detects endogenous levels of ZFYVE19 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
471
Applicable Applications for anti-ZFYVE19 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 300-350 of Human ZFYVE19.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of ZFYVE19 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysate (40ug) Lane2:MCF-7 whole cell lysate (40ug) Lane3:HEK293T whole cell lysate (40ug) Lane4:L02 whole cell lysate (20ug))
Western Blot (WB)
(Western Blot (WB) analysis of ZFYVE19 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysate (40ug) Lane2:MCF-7 whole cell lysate (40ug) Lane3:HEK293T whole cell lysate (40ug) Lane4:L02 whole cell lysate (20ug))
Related Product Information for anti-ZFYVE19 antibody
Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZFYVE19 (zinc finger, FYVE domain containing 19), also known as MPFYVE (MLL partner containing FYVE domain), is a 471 amino acid protein that contains one FYVE-type zinc finger. Expressed in heart, brain, kidney, skeletal muscle and liver, ZFYVE19 may participate in transcriptional regulation events within the cell. Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML), a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever, anemia, bone pain, shortness of breath and frequent infections. Three isoforms of ZFYVE19 exist due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 52kDa
NCBI Official Full Name
abscission/NoCut checkpoint regulator isoform 1
UniProt Protein Name
Zinc finger FYVE domain-containing protein 19
Protein Family
UniProt Gene Name
ZFYVE19
UniProt Synonym Gene Names
MPFYVE
UniProt Entry Name
ZFY19_HUMAN
Uniprot Description
ZFYVE19: A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Oncoprotein
Chromosomal Location of Human Ortholog: 15q15.1
Cellular Component: centrosome; cytoplasm; midbody; cleavage furrow
Molecular Function: protein binding; zinc ion binding; phosphatidylinositol 3-phosphate binding
Biological Process: cell division; abscission; cell cycle; negative regulation of cytokinesis
Similar Products
Product Notes
The ZFYVE19 zfyve19 (Catalog #AAA3007632) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZFYVE19 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZFYVE19 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the ZFYVE19 zfyve19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZFYVE19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
