Western Blot (WB)
(Western Blot (WB) analysis of MINA polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:NIH-3T3 whole cell lysateLane3:PC12 whole cell lysate)
Rabbit MINA Polyclonal Antibody | anti-MINA antibody
MINA Polyclonal Antibody
Gene Names
RIOX2; ROX; MDIG; MINA; NO52; JMJD10; MINA53
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
MINA; Polyclonal Antibody; MINA Polyclonal Antibody; Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; 60S ribosomal protein L27a histidine hydroxylase; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; Ribosomal oxygenase MINA; ROX; MDIG; MINA53; NO52; anti-MINA antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MINA polyclonal antibody detects endogenous levels of MINA protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
465
Applicable Applications for anti-MINA antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human MINA.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of MINA polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:NIH-3T3 whole cell lysateLane3:PC12 whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of MINA polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:NIH-3T3 whole cell lysateLane3:PC12 whole cell lysate)
Related Product Information for anti-MINA antibody
Mina53, also known as MINA (MYC induced nuclear antigen), MDIG or NO52, is a 465 amino acid protein that contains one JmjC domain and localizes to the nucleus. Expressed in placenta, liver, heart, pancreas and skeletal muscle, Mina53 is thought to be involved in ribosome biogenesis, specifically in the assembly of pre-ribosomal particles. Via its involvement in ribosome biogenesis, Mina53 may play an important role in cell growth and survival, as well as overall cellular proliferation events. Mina53 expression is upregulated in esophageal squamous cell carcinoma (ESCC), colon cancer and lung cancer tissues, suggesting that Mina53 may be involved in tumorigenesis. Multiple isoforms of Mina53 exist due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 53kDa
NCBI Official Full Name
Ribosomal oxygenase 2
NCBI Official Synonym Full Names
ribosomal oxygenase 2
NCBI Official Symbol
RIOX2
NCBI Official Synonym Symbols
ROX; MDIG; MINA; NO52; JMJD10; MINA53
NCBI Protein Information
ribosomal oxygenase 2
UniProt Protein Name
Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA
UniProt Gene Name
MINA
UniProt Synonym Gene Names
ROX
UniProt Entry Name
MINA_HUMAN
NCBI Description
MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008]
Uniprot Description
MINA: Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. Belongs to the MINA53/NO66 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus
Chromosomal Location of Human Ortholog: 3q11.2
Cellular Component: transcription factor complex; cytoplasm; nucleolus; cytosol; nucleus
Molecular Function: dioxygenase activity; metal ion binding
Biological Process: transcription, DNA-dependent; ribosome biogenesis and assembly; negative regulation of transcription from RNA polymerase II promoter
Research Articles on MINA
Similar Products
Product Notes
The MINA mina (Catalog #AAA3006525) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MINA Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MINA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the MINA mina for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MINA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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