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Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using NUDT6 antibody.)

Rabbit anti-Human, Mouse OLFM1 Polyclonal Antibody | anti-OLFM1 antibody

OLFM1 Polyclonal Antibody

Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
OLFM1; Polyclonal Antibody; OLFM1 Polyclonal Antibody; AMY; NEUROBLASTOMA PROTEIN; Neuronal olfactomedin-related ER localized protein; Noe1; NOE1; Noel; Noel1; Noelin; Noelin1; OlfA; Olfactomedin 1; Olfactomedin-1; Olfm1; Pancortin 1; Pancortin; anti-OLFM1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
OLFM1 polyclonal antibody detects endogenous levels of OLFM1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
485
Applicable Applications for anti-OLFM1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant full length Human OLFM1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using NUDT6 antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using NUDT6 antibody.)
Related Product Information for anti-OLFM1 antibody
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
~ 72kDa
NCBI Official Full Name
Noelin
UniProt Protein Name
Noelin
Protein Family
UniProt Gene Name
OLFM1
UniProt Synonym Gene Names
NOE1; NOEL1
UniProt Entry Name
NOE1_HUMAN

Uniprot Description

OLFM1: Seems to play an important role in regulating the production of neural crest cells by the neural tube. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Cell adhesion

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: extracellular space; synapse; cell junction

Molecular Function: protein binding; beta-amyloid binding

Biological Process: nervous system development; protein oligomerization

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Product Notes

The OLFM1 olfm1 (Catalog #AAA3006329) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OLFM1 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's OLFM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the OLFM1 olfm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OLFM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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