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Western Blot (WB) (Western Blot (WB) analysis of Hox-B2 (P67) pAb at 1:1000 dilutionLane1:K562 whole cell lysate (40ug) Lane2:The Embryo tissue lysate of Mouse (20ug) Lane3:PC12 whole cell lysate (10ug) Lane4:Hela whole cell lysate (40ug))

Rabbit Hox-B2 Polyclonal Antibody | anti-Hox-B2 antibody

Hox-B2 (P67) Polyclonal Antibody

Gene Names
HOXB2; K8; HOX2; HOX2H; Hox-2.8
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
Hox-B2; Polyclonal Antibody; Hox-B2 (P67) Polyclonal Antibody; Homeobox protein Hox-B2; Homeobox protein Hox-2.8; Homeobox protein Hox-2H; K8; HOX2H; HOXB2; anti-Hox-B2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
HoxB2 (P67) polyclonal antibody detects endogenous levels of HoxB2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
356
Applicable Applications for anti-Hox-B2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 30-80 of Human Hox-B2.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of Hox-B2 (P67) pAb at 1:1000 dilutionLane1:K562 whole cell lysate (40ug) Lane2:The Embryo tissue lysate of Mouse (20ug) Lane3:PC12 whole cell lysate (10ug) Lane4:Hela whole cell lysate (40ug))

Western Blot (WB) (Western Blot (WB) analysis of Hox-B2 (P67) pAb at 1:1000 dilutionLane1:K562 whole cell lysate (40ug) Lane2:The Embryo tissue lysate of Mouse (20ug) Lane3:PC12 whole cell lysate (10ug) Lane4:Hela whole cell lysate (40ug))
Related Product Information for anti-Hox-B2 antibody
Hoxb-1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the sonic hedgehog and Mash1 signaling pathways. Hoxb2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. Hoxb2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, Hoxb2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 38kDa
NCBI Official Full Name
homeobox protein Hox-B2
NCBI Official Synonym Full Names
homeobox B2
NCBI Official Symbol
HOXB2
NCBI Official Synonym Symbols
K8; HOX2; HOX2H; Hox-2.8
NCBI Protein Information
homeobox protein Hox-B2
UniProt Protein Name
Homeobox protein Hox-B2
UniProt Gene Name
HOXB2
UniProt Synonym Gene Names
HOX2H
UniProt Entry Name
HXB2_HUMAN

NCBI Description

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. [provided by RefSeq, Jul 2008]

Uniprot Description

HOXB2: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: cytoplasm; nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: anterior/posterior pattern formation; facial nerve structural organization; transcription, DNA-dependent; regulation of transcription, DNA-dependent; dorsal/ventral pattern formation; blood circulation; multicellular organismal development; morphogenesis of an epithelial sheet; rhombomere 4 development; rhombomere 3 development; neural nucleus development; embryonic skeletal morphogenesis

Research Articles on Hox-B2

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Product Notes

The Hox-B2 hoxb2 (Catalog #AAA3004411) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Hox-B2 (P67) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Hox-B2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the Hox-B2 hoxb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hox-B2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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