Rabbit TBX10 Polyclonal Antibody | anti-TBX10 antibody

TBX10 (P291) Polyclonal Antibody

Cat. Num. AAA3002771

• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: TBX10; Polyclonal Antibody; TBX10 (P291) Polyclonal Antibody; T-box transcription factor TBX10; T-box protein 10; TBX7; anti-TBX10 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: TBX10 (P291) polyclonal antibody detects endogenous levels of TBX10 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 385

• Applicable Applications for anti-TBX10 antibody: Immunohistochemistry (IHC)
• Application Notes: IHC: 1:50-1:200
• Immunogen: Synthetic peptide, corresponding to amino acids 261-310 of Human TBX10.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Testing Data

Related Product Information for anti-TBX10 antibody

The T-box (Tbx) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The Tbx gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. Tbx genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in Tbx genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/Brachyury, which is a transcription activator.

NCBI and Uniprot Product Information

• NCBI GI #: 32567784
• NCBI Accession #: NP_005986.2
• NCBI GenBank Nucleotide #: NP_005986.2
• UniProt Accession #: O75333
• Molecular Weight: ~ 42kDa
• NCBI Official Full Name: T-box transcription factor TBX10
• UniProt Protein Name: T-box transcription factor TBX10
• Protein Family: T-box transcription factor
• UniProt Gene Name: TBX10
• UniProt Synonym Gene Names: TBX7; T-box protein 10
• UniProt Entry Name: TBX10_HUMAN

Uniprot Description

TBX10: Probable transcriptional regulator involved in developmental processes.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; anatomical structure morphogenesis; transcription, DNA-dependent