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RND1 / Rho-Related GTP-Binding Protein Rho6 Recombinant Protein | RND1 recombinant protein

Human RND1 / Rho-Related GTP-Binding Protein Rho6 Recombinant Protein

Gene Names
RND1; ARHS; RHO6; RHOS
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
RND1 / Rho-Related GTP-Binding Protein Rho6; Human RND1 / Rho-Related GTP-Binding Protein Rho6 Recombinant Protein; Rho-related GTP-binding protein Rho6; Rho family GTPase 1; Rnd1; RHO6; RND1 recombinant protein
Ordering
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
232
Applicable Applications for RND1 recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Binds GRB7 and PLXNB1. Interacts with UBXD5. Interacts with PLXNA2.
Entry Function
Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
rho-related GTP-binding protein Rho6
NCBI Official Synonym Full Names
Rho family GTPase 1
NCBI Official Symbol
RND1
NCBI Official Synonym Symbols
ARHS; RHO6; RHOS
NCBI Protein Information
rho-related GTP-binding protein Rho6
UniProt Protein Name
Rho-related GTP-binding protein Rho6
UniProt Gene Name
RND1
UniProt Synonym Gene Names
RHO6
UniProt Entry Name
RND1_HUMAN

NCBI Description

This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014]

Uniprot Description

RND1: Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein, monomeric, Rho; G protein, monomeric; G protein

Chromosomal Location of Human Ortholog: 12q12

Cellular Component: cytoskeleton; adherens junction; plasma membrane; cytosol

Molecular Function: GTPase activity; protein binding; GTP binding; receptor binding

Biological Process: axon guidance; metabolic process; small GTPase mediated signal transduction; actin filament organization; negative regulation of cell adhesion; neuron remodeling

Research Articles on RND1

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Product Notes

The RND1 rnd1 (Catalog #AAA2903009) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's RND1 / Rho-Related GTP-Binding Protein Rho6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the RND1 rnd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RND1 / Rho-Related GTP-Binding Protein Rho6, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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