NCBI and Uniprot Product Information
NCBI Description
a highly selective urate transporter/channel [RGD, Feb 2006]
Uniprot Description
galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Cellular Component: cytoplasm; extracellular region; extracellular space; intracellular; nucleus
Molecular Function: carbohydrate binding; disaccharide binding; enzyme binding; galactoside binding; protein serine/threonine kinase activator activity; receptor binding; signal transducer activity
Biological Process: activation of NF-kappaB transcription factor; female pregnancy; inflammatory response; ion transport; maintenance of protein localization; maternal process involved in pregnancy; natural killer cell tolerance induction; negative regulation of activated T cell proliferation; negative regulation of chemokine production; negative regulation of inflammatory response; negative regulation of interferon-gamma production; negative regulation of mast cell degranulation; negative regulation of natural killer cell activation; negative regulation of natural killer cell degranulation; negative regulation of natural killer cell mediated cytotoxicity; negative regulation of tumor necrosis factor production; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response; positive regulation of chemokine production; positive regulation of cytokine production; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of innate immune response; positive regulation of interleukin-1 beta secretion; positive regulation of interleukin-1 production; positive regulation of interleukin-4 production; positive regulation of macrophage activation; positive regulation of NF-kappaB import into nucleus; positive regulation of oxidoreductase activity; positive regulation of regulatory T cell differentiation; positive regulation of tumor necrosis factor production; positive regulation of virion penetration into host cell; regulation of interleukin-4 production; regulation of interleukin-5 production; regulation of natural killer cell differentiation; regulation of T cell differentiation in the thymus; response to lipopolysaccharide; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway
Research Articles on Lgals9
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Product Notes
The Rat Lgals9 lgals9 (Catalog #AAA2886145) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886145 ELISA Kit recognizes Rat Lgals9. It is sometimes possible for the material contained within the vial of "Galectin-9, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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