Signal-induced proliferation-associated 1-like protein 1 ELISA Kit | Sipa1l1 elisa kit

Rat Signal-induced proliferation-associated 1-like protein 1 ELISA Kit

Cat. Num. AAA2883479

• Gene Names: Sipa1l1; SPAL; Spa1; Spar; Spa-1
• Reactivity: Rat
• Synonyms: Signal-induced proliferation-associated 1-like protein 1; Rat Signal-induced proliferation-associated 1-like protein 1 ELISA Kit; SIPA1-like protein 1; SPA-1-like protein p1294; Spine-associated Rap GTPase-activating protein; SPAR; Sipa1l1; Spa1; Sipa1l1 elisa kit

• Reactivity: Rat
• Sequence Length: 1822

• Assay Type: Sandwich
• Detection Range: 0.156-10 ng/mL
• Sensitivity: 0.081 ng/mL
• Intra-Assay CV: <=4.3%
• Inter-Assay CV: <=8.4%
• Recovery: 87%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 21326463
• NCBI GeneID: 246212
• NCBI Accession #: NP_647546.1
• NCBI GenBank Nucleotide #: NM_139330.1
• UniProt Accession #: O35412
• Molecular Weight: 201,925 Da
• NCBI Official Full Name: signal-induced proliferation-associated 1-like protein 1
• NCBI Official Synonym Full Names: signal-induced proliferation-associated 1 like 1
• NCBI Official Symbol: Sipa1l1
• NCBI Official Synonym Symbols: SPAL; Spa1; Spar; Spa-1
• NCBI Protein Information: signal-induced proliferation-associated 1-like protein 1
• UniProt Protein Name: Signal-induced proliferation-associated 1-like protein 1
• Protein Family: Signal-induced proliferation-associated 1-like protein
• UniProt Gene Name: Sipa1l1
• UniProt Synonym Gene Names: Spa1; SIPA1-like protein 1; SPAR
• UniProt Entry Name: SI1L1_RAT

NCBI Description

GTPase-activating protein (GAP) that is specific for Rap1; may be involved in cytoskeletal organization of neurons [RGD, Feb 2006]

Uniprot Description

SIPA1L1: Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F- actin. Contributes to the regulation of dendritic spine morphogenesis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, Ras; GAPs

Cellular Component: cell junction; cell soma; cytoplasm; cytoskeleton; dendritic spine; postsynaptic density; postsynaptic membrane; protein complex

Molecular Function: actin filament binding; ephrin receptor binding; GTPase activator activity; protein binding; protein complex binding; protein kinase binding; ubiquitin protein ligase binding

Biological Process: actin cytoskeleton reorganization; ephrin receptor signaling pathway; positive regulation of GTPase activity; regulation of axonogenesis; regulation of dendrite morphogenesis; regulation of GTPase activity; regulation of small GTPase mediated signal transduction; regulation of synaptic plasticity