Typical Testing Data/Standard Curve (for reference only)
Mouse Thioredoxin (Trx) ELISA Kit | Trx elisa kit
Mouse Thioredoxin (Trx) ELISA Kit
No significant cross-reactivity or interference between Thioredoxin (Trx) and analogues was observed.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
protein-disulfide reductase enzyme that is important for redox signalling during apoptosis and cell growth [RGD, Feb 2006]
Uniprot Description
TXN: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3. In case of infection, interacts with S.typhimurium protein slrP. Interacts with APEX1; the interaction stimulates the FOS/JUN AP-1 DNA- binding activity in a redox-dependent manner. Up-regulated by ionizing radiation. Belongs to the thioredoxin family.
Protein type: Nuclear receptor co-regulator
Cellular Component: cell soma; mitochondrion; axon; dendrite; cytoplasm; extracellular region; nucleus; cytosol
Molecular Function: thioredoxin-disulfide reductase activity; enzyme binding; protein disulfide oxidoreductase activity; peptide disulfide oxidoreductase activity
Biological Process: response to drug; negative regulation of protein export from nucleus; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation; glycerol ether metabolic process; response to radiation; response to selenium ion; regulation of transcription, DNA-dependent; cell redox homeostasis; regulation of protein import into nucleus, translocation; response to axon injury; response to activity; positive regulation of DNA binding
Research Articles on Trx
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Product Notes
The Mouse Trx txn (Catalog #AAA2019144) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2019144 ELISA Kit recognizes Mouse Trx. It is sometimes possible for the material contained within the vial of "Thioredoxin (Trx), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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