Typical Testing Data/Standard Curve (for reference only)
Rat Follistatin-related protein 3 ELISA Kit | Fstl3 elisa kit
Rat Follistatin-related protein 3 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
may have a role in spermatogenesis [RGD, Feb 2006]
Uniprot Description
FSTL3: Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10. A chromosomal aberration involving FSTL3 is found in a case of B-cell chronic lymphocytic leukemia. Translocation t(11;19)(q13;p13) with CCDN1. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: Secreted, signal peptide; Secreted; Oncoprotein
Cellular Component: extracellular space; Golgi apparatus; nucleoplasm; nucleus; secretory granule
Molecular Function: activin binding; fibronectin binding
Biological Process: adrenal gland development; hemopoietic progenitor cell differentiation; kidney development; lung development; male gonad development; negative regulation of activin receptor signaling pathway; negative regulation of BMP signaling pathway; negative regulation of osteoclast differentiation; ossification; positive regulation of cell-cell adhesion; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; spermatogenesis; transcription, DNA-dependent
Research Articles on Fstl3
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Product Notes
The Rat Fstl3 fstl3 (Catalog #AAA2883428) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883428 ELISA Kit recognizes Rat Fstl3. It is sometimes possible for the material contained within the vial of "Follistatin-related protein 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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