Mouse ATP-dependent RNA helicase DDX42 ELISA Kit | Ddx42 elisa kit
Mouse ATP-dependent RNA helicase DDX42 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
DDX42: ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm. Belongs to the DEAD box helicase family. DDX42 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.13; Helicase
Cellular Component: cytoplasm; membrane; nucleoplasm; nucleus
Molecular Function: ATP binding; ATP-dependent RNA helicase activity; helicase activity; hydrolase activity; nucleic acid binding; nucleotide binding; RNA binding
Biological Process: protein localization; RNA secondary structure unwinding
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Product Notes
The Mouse Ddx42 ddx42 (Catalog #AAA2883151) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883151 ELISA Kit recognizes Mouse Ddx42. It is sometimes possible for the material contained within the vial of "ATP-dependent RNA helicase DDX42, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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