Typical Testing Data/Standard Curve (for reference only)
Mouse Platelet-derived growth factor subunit B ELISA Kit | Pdgfb elisa kit
Mouse Platelet-derived growth factor subunit B ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
PDGFB: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. A chromosomal aberration involving PDGFB is found in dermatofibrosarcoma protuberans. Translocation t(17;22)(q22;q13) with PDGFB. Belongs to the PDGF/VEGF growth factor family.
Protein type: Oncoprotein; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Cellular Component: basolateral plasma membrane; cell soma; cell surface; cytoplasm; dendrite; extracellular region; extracellular space; membrane
Molecular Function: chemoattractant activity; collagen binding; growth factor activity; identical protein binding; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; protein homodimerization activity; receptor binding; superoxide-generating NADPH oxidase activator activity
Biological Process: actin cytoskeleton organization and biogenesis; activation of protein kinase activity; activation of protein kinase B; blood vessel morphogenesis; cell projection biogenesis; embryonic placenta development; eye photoreceptor cell development; glial cell development; heart development; monocyte chemotaxis; multicellular organismal development; negative regulation of cell migration; negative regulation of phosphatidylinositol biosynthetic process; negative regulation of protein binding; negative regulation of transcription, DNA-dependent; negative regulation of vasodilation; neuron remodeling; peptidyl-serine phosphorylation; peptidyl-tyrosine phosphorylation; platelet-derived growth factor receptor signaling pathway; positive chemotaxis; positive regulation of blood vessel endothelial cell migration; positive regulation of cell division; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of chemotaxis; positive regulation of collagen biosynthetic process; positive regulation of cyclin-dependent protein kinase activity; positive regulation of DNA replication; positive regulation of endothelial cell proliferation; positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of fibroblast proliferation; positive regulation of glomerular filtration; positive regulation of MAP kinase activity; positive regulation of MAPKKK cascade; positive regulation of mitosis; positive regulation of mitotic cell cycle, embryonic; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase activity; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein amino acid autophosphorylation; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; positive regulation of vasoconstriction; protein amino acid phosphorylation; regulation of peptidyl-tyrosine phosphorylation; response to wounding; retina development in camera-type eye; substrate-bound cell migration; synaptogenesis
Research Articles on Pdgfb
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Product Notes
The Mouse Pdgfb pdgfb (Catalog #AAA2882226) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882226 ELISA Kit recognizes Mouse Pdgfb. It is sometimes possible for the material contained within the vial of "Platelet-derived growth factor subunit B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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