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Canine Rab GDP dissociation inhibitor beta (GDI2) ELISA Kit | GDI2 elisa kit

Canine Rab GDP dissociation inhibitor beta (GDI2) ELISA Kit

Gene Names
GDI2; GDI-2
Reactivity
Canine
Synonyms
Rab GDP dissociation inhibitor beta (GDI2); Canine Rab GDP dissociation inhibitor beta (GDI2) ELISA Kit; RP11-318E3.2; FLJ16452; FLJ37352; RABGDIB; rab GDP-dissociation inhibitor; beta; GDI2 elisa kit
Ordering
For Research Use Only!
Reactivity
Canine
Specificity
This assay has high sensitivity and excellent specificity for detection of Canine GDI2. No significant cross-reactivity or interference between Canine GDI2 and analogues was observed.
Sequence Length
445
Assay Type
Quantitive Sandwich
Samples
Serum, Plasma, Other Biological Fluids
Detection Wavelength
450 nm
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%)
= SD/meanX100
Intra-Assay
CV
Inter-Assay
CV
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for GDI2 elisa kit
Description: This assay employs a two-site sandwich ELISA to quantitate GDI2 in samples. An antibody specific for GDI2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GDI2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for GDI2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GDI2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Overview: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.
Bachner et al. (1995) studied expression patterns of the 2 human genes. They showed that the 2.5-kb mRNA for RABGDIB is ubiquitously expressed, in contrast to RABGDIA, which is expressed primarily in neural and sensory tissues.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,322 Da
NCBI Official Full Name
rab GDP dissociation inhibitor beta
NCBI Official Synonym Full Names
GDP dissociation inhibitor 2
NCBI Official Symbol
GDI2
NCBI Official Synonym Symbols
GDI-2
NCBI Protein Information
rab GDP dissociation inhibitor beta
UniProt Protein Name
Rab GDP dissociation inhibitor beta
UniProt Gene Name
GDI2
UniProt Synonym Gene Names
Rab GDI beta; GDI-2

Uniprot Description

Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.

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Product Notes

The Canine GDI2 gdi2 (Catalog #AAA287640) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA287640 ELISA Kit recognizes Canine GDI2. It is sometimes possible for the material contained within the vial of "Rab GDP dissociation inhibitor beta (GDI2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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