Human Kidney injury molecule 1 ELISA Kit | Kim-1 elisa kit
Human Kidney injury molecule 1 (Kim-1) ELISA Kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate Kim-1 in Human serum, plasma, urine. An antibody specific for Kim-1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any Kim-1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for Kim-1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of Kim-1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19. [provided by RefSeq, Apr 2015]
Uniprot Description
TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q33.3
Cellular Component: integral component of membrane
Molecular Function: viral receptor activity
Biological Process: entry of virus into host cell
Disease: Ige Responsiveness, Atopic
Research Articles on Kim-1
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Product Notes
The Human Kim-1 havcr1 (Catalog #AAA285721) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA285721 ELISA Kit recognizes Human Kim-1. It is sometimes possible for the material contained within the vial of "Kidney injury molecule 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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