Bovine Coxsackievirus and adenovirus receptor ELISA Kit | CXADR elisa kit

Bovine Coxsackievirus and adenovirus receptor (CXADR) ELISA Kit

Cat. Num. AAA285367

• Reactivity: Bovine
• Synonyms: Coxsackievirus and adenovirus receptor; Bovine Coxsackievirus and adenovirus receptor (CXADR) ELISA Kit; CXCL1; GRO1; GROa; GRO-A; MGSA-A; NAP3; SCYB1; Chemokine C-X-C-Motif Ligand 1; Melanoma Growth Stimulating Activity Alpha; Fibroblast Secretory Protein; CXADR elisa kit

• Reactivity: Bovine
• Specificity: This assay has high sensitivity and excellent specificity for detection of Bovine CXADR. No significant cross-reactivity or interference between Bovine CXADR and analogues was observed.
• Sequence Length: 365

• Samples: Serum, Plasma, Other biological fluids
• Assay Type: Sandwich
• Sample Volume: 1-200 uL
• Precision: Intra-assay Precision (Precision within an assay); Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.; Inter-assay Precision (Precision between assays); Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.; CV (%) = SD/meanX100; Intra-Assay: CV; Inter-Assay: CV
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 2-8 degree C.

Related Product Information for CXADR elisa kit

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate CXADR in samples. An antibody specific for CXADR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyCXADR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CXADR is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CXADR bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 27805839
• NCBI GeneID: 281733
• NCBI Accession #: NP_776723.1
• NCBI GenBank Nucleotide #: NM_174298.4
• UniProt Accession #: Q8WMV3; Q3SZH9
• Molecular Weight: 40,153 Da
• NCBI Official Full Name: coxsackievirus and adenovirus receptor homolog
• NCBI Official Symbol: CXADR
• NCBI Protein Information: coxsackievirus and adenovirus receptor homolog
• UniProt Protein Name: Coxsackievirus and adenovirus receptor homolog
• Protein Family: Coxsackievirus and adenovirus receptor
• UniProt Gene Name: CXADR
• UniProt Synonym Gene Names: CAR; Coxsackie virus and adenovirus receptor

Uniprot Description

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair ().