Rabbit anti-Human WDHD1 Polyclonal Antibody | anti-WDHD1 antibody

WDHD1 Polyclonal Antibody

Cat. Num. AAA2561467

• Gene Names: WDHD1; AND1; CTF4; AND-1; CHTF4
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: WDHD1; Polyclonal Antibody; WDHD1 Polyclonal Antibody; Acidic nucleoplasmic DNA binding protein 1; And 1; And1; WD repeat and HMG box DNA binding protein 1; WDHD 1; anti-WDHD1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 0.9mg/mL (varies by lot)
• Sequence Length: 1129

• Applicable Applications for anti-WDHD1 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:25-1:100; ELISA: 1:5000-1:10000
• Immunogen: Synthetic peptide of human WDHD1
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using WDHD1 Polyclonal Antibody at dilution of 1:35(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human tonsil tissue using WDHD1 Polyclonal Antibody at dilution of 1:35(×200))

Related Product Information for anti-WDHD1 antibody

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms.WDHD1 (WD Repeat And HMG-Box DNA Binding Protein 1) is a Protein Coding gene. Diseases associated with WDHD1 include Trench Fever. Among its related pathways are Mesodermal Commitment Pathway. GO annotations related to this gene include RNA binding and RNA polymerase binding.

Product Categories/Family for anti-WDHD1 antibody

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 5901892
• NCBI GeneID: 11169
• NCBI Accession #: NP_009017.1
• NCBI GenBank Nucleotide #: NP_009017.1
• UniProt Accession #: O75717
• NCBI Official Full Name: WD repeat and HMG-box DNA-binding protein 1 isoform 1
• NCBI Official Synonym Full Names: WD repeat and HMG-box DNA binding protein 1
• NCBI Official Symbol: WDHD1
• NCBI Official Synonym Symbols: AND1; CTF4; AND-1; CHTF4
• NCBI Protein Information: WD repeat and HMG-box DNA-binding protein 1
• UniProt Protein Name: WD repeat and HMG-box DNA-binding protein 1
• Protein Family: WD repeat and HMG-box DNA-binding protein
• UniProt Gene Name: WDHD1
• UniProt Synonym Gene Names: AND1; And-1
• UniProt Entry Name: WDHD1_HUMAN

NCBI Description

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

WDHD1: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 14q22.2

Cellular Component: nucleoplasm; cytoplasm; chromosome, pericentric region

Molecular Function: protein binding; DNA binding; RNA binding; chromatin binding

Biological Process: RNA processing; regulation of chromosome organization and biogenesis