Rabbit WDHD1 Polyclonal Antibody | anti-WDHD1 antibody

WDHD1 Antibody

Cat. Num. AAA5315472

• Gene Names: WDHD1; AND1; CTF4; AND-1; CHTF4
• Applications: Western Blot, Immunohistochemistry
• Purity: Immunogen Affinity Chromatography
• Synonyms: WDHD1; Polyclonal Antibody; WDHD1 Antibody; Purified Polyclonal WDHD1 Antibody; Polyclonal WDHD1 antibody; Anti-WDHD1 antibody; AND1 antibody; WD repeat and HMG-box DNA-binding protein 1 antibody; Acidic nucleoplasmic DNA-binding protein 1 antibody; And-1 antibody; anti-WDHD1 antibody

• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of WDHD1 protein
• Purity/Purification: Immunogen Affinity Chromatography
• Form/Format: Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
• Sequence Length: 1006

• Applicable Applications for anti-WDHD1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:1000; IHC: 1:100-1:200
• Immunogen: WDHD1 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human WDHD1 as the immunogen
• Preparation and Storage: Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of WDHD1 expression in HeLa (A); HEK293T (B) whole cell lysates.)

Related Product Information for anti-WDHD1 antibody

WDHD1 contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.

Product Categories/Family for anti-WDHD1 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 56550086
• NCBI GeneID: 11169
• NCBI GenBank Nucleotide #: NP_001008397.1
• UniProt Accession #: O75717
• NCBI Official Full Name: WD repeat and HMG-box DNA-binding protein 1 isoform 2
• NCBI Official Synonym Full Names: WD repeat and HMG-box DNA binding protein 1
• NCBI Official Symbol: WDHD1
• NCBI Official Synonym Symbols: AND1; CTF4; AND-1; CHTF4
• NCBI Protein Information: WD repeat and HMG-box DNA-binding protein 1
• UniProt Protein Name: WD repeat and HMG-box DNA-binding protein 1
• Protein Family: WD repeat and HMG-box DNA-binding protein
• UniProt Gene Name: WDHD1
• UniProt Synonym Gene Names: AND1; And-1
• UniProt Entry Name: WDHD1_HUMAN

NCBI Description

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

WDHD1: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 14q22.2

Cellular Component: nucleoplasm; cytoplasm; chromosome, pericentric region

Molecular Function: protein binding; DNA binding; RNA binding; chromatin binding

Biological Process: RNA processing; regulation of chromosome organization and biogenesis