Rabbit IGF2BP2 Polyclonal Antibody | anti-IGF2BP2 antibody

IGF2BP2 Rabbit Polyclonal

Cat. Num. AAA7600405

• Gene Names: IGF2BP2; IMP2; IMP-2; VICKZ2
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: IGF2BP2; Polyclonal Antibody; IGF2BP2 Rabbit Polyclonal; anti-IGF2BP2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 599

• Applicable Applications for anti-IGF2BP2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Immunogen: Insulin-like growth factor 2 mRNA binding protein 2
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse liver using MBS7600405 (IGF2BP2 antibody) at dilution of 1:50)

Western Blot (WB)

(human kidney tissue were subjected to SDS PAGE followed by western blot with MBS7600405 (IGF2BP2 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 64085377
• NCBI GeneID: 10644
• NCBI Accession #: NP_006539.3
• NCBI GenBank Nucleotide #: NM_006548.4
• Molecular Weight: 58,578 Da
• NCBI Official Full Name: insulin-like growth factor 2 mRNA-binding protein 2 isoform a
• NCBI Official Synonym Full Names: insulin like growth factor 2 mRNA binding protein 2
• NCBI Official Symbol: IGF2BP2
• NCBI Official Synonym Symbols: IMP2; IMP-2; VICKZ2
• NCBI Protein Information: insulin-like growth factor 2 mRNA-binding protein 2
• UniProt Protein Name: Insulin-like growth factor 2 mRNA-binding protein 2
• Protein Family: Insulin-like growth factor 2 mRNA-binding protein
• UniProt Gene Name: IGF2BP2
• UniProt Synonym Gene Names: IMP2; VICKZ2; IGF2 mRNA-binding protein 2; IMP-2
• UniProt Entry Name: IF2B2_HUMAN

NCBI Description

This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms. [provided by RefSeq, May 2014]

Uniprot Description

IGF2BP2: Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs. Belongs to the RRM IMP/VICKZ family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Translation

Chromosomal Location of Human Ortholog: 3q27.2

Cellular Component: cytoplasm; cytoskeleton; cytosol; nucleus

Molecular Function: mRNA 3'-UTR binding; mRNA 5'-UTR binding; protein binding; translation regulator activity

Biological Process: anatomical structure morphogenesis; gene expression; negative regulation of translation; regulation of cytokine biosynthetic process

Disease: Diabetes Mellitus, Noninsulin-dependent