Western Blot (WB)
(Western Blot analysis of A431 cell using TRAF4AF1 Polyclonal Antibody at dilution of 1:500)
Rabbit anti-Human C15orf23 Polyclonal Antibody | anti-C15orf23 antibody
C15orf23 Polyclonal Antibody
Western Blot (WB)
(Western Blot analysis of A431 cell using TRAF4AF1 Polyclonal Antibody at dilution of 1:500)
Western Blot (WB)
(Western Blot analysis of A431 cell using TRAF4AF1 Polyclonal Antibody at dilution of 1:500)
NCBI and Uniprot Product Information
Observed: 35 kDa
Uniprot Description
Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase (PubMed:19667759). Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture (PubMed:19667759, PubMed:22110139). The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments (PubMed:21402792). Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division (PubMed:23035123). May be involved in UV-induced apoptosis via its interaction with PRPF19; however, these results need additional evidences (PubMed:24718257).
Research Articles on C15orf23
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Product Notes
The C15orf23 knstrn (Catalog #AAA2554027) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C15orf23 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C15orf23 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the C15orf23 knstrn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C15orf23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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