Western Blot (WB)
(Western Blot analysis of pig pancreas tissue using PLA2G1B Monoclonal Antibody at dilution of 1:3000)
Mouse anti-Human PLA2G1B Monoclonal Antibody | anti-PLA2G1B antibody
PLA2G1B Monoclonal Antibody
Gene Names
PLA2G1B; PLA2; PLA2A; PPLA2
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein A Purification
Synonyms
PLA2G1B; Monoclonal Antibody; PLA2G1B Monoclonal Antibody; Group IB phospholipase A2; Phospholipase A2; PLA2; PLA2A; PPLA2; anti-PLA2G1B antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
1F2C10
Purity/Purification
Protein A Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
453
Applicable Applications for anti-PLA2G1B antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1500-1:6000
IHC: 1:100-1:400
IHC: 1:100-1:400
Immunogen
Fusion Protein of PLA2G1B
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of pig pancreas tissue using PLA2G1B Monoclonal Antibody at dilution of 1:3000)
Western Blot (WB)
(Western Blot analysis of pig pancreas tissue using PLA2G1B Monoclonal Antibody at dilution of 1:3000)
Related Product Information for anti-PLA2G1B antibody
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. PLA2G1B (Phospholipase A2 Group IB) is a Protein Coding gene. Diseases associated with PLA2G1B include Distal Hereditary Motor Neuropathy, Type Ii. Among its related pathways are Linoleic acid metabolism and Vascular smooth muscle contraction. GO annotations related to this gene include calcium ion binding and phospholipase A2 activity. An important paralog of this gene is PLA2G2D.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Calculated Molecular Weight: 70aa; 8kDa; 148aa; 16kDa
Observed Molecular Weight: 16kDa
Observed Molecular Weight: 16kDa
NCBI Official Full Name
Homo sapiens phospholipase A2, group IB (pancreas), mRNA
NCBI Official Synonym Full Names
phospholipase A2 group IB
NCBI Official Symbol
PLA2G1B
NCBI Official Synonym Symbols
PLA2; PLA2A; PPLA2
NCBI Protein Information
phospholipase A2
UniProt Protein Name
Phospholipase A(2)
Protein Family
UniProt Gene Name
PLA2G1B
NCBI Description
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]
Research Articles on PLA2G1B
Similar Products
Product Notes
The PLA2G1B pla2g1b (Catalog #AAA2549124) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PLA2G1B Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLA2G1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1500-1:6000 IHC: 1:100-1:400. Researchers should empirically determine the suitability of the PLA2G1B pla2g1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLA2G1B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
