SDS-PAGE
FCGRT & B2M Heterodimer Recombinant Protein | FCGRT recombinant protein
Recombinant Rat FCGRT & B2M Heterodimer Protein
Gene Names
Fcgrt; FcRn
Purity
> 98 % as determined by SDS-PAGE
Synonyms
FCGRT & B2M Heterodimer; Recombinant Rat FCGRT & B2M Heterodimer Protein; FCGRT FCRN & B2M; FCGRT recombinant protein
Host
Human Cells
Purity/Purification
> 98 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
366
Application Notes
The recombinant heterodimer of rat FCGRT & B2M comprises 386 (287+99) amino acids and has a calculated molecular mass of 44 (32.4+ 11.6) KDa. The apparent molecular mass of rat FCGRT & B2M heterodimer is approximately 35 & 12 KDa respectively in SDS-PAGE.
Predicted N Terminal
Ala 23 & Ile 21
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for FCGRT recombinant protein
A DNA sequence encoding the extracellular domain (Met 1-Ser 298) of rat FCGRT (P13599) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the rat B2M (P07151) (Met 1-Met 119) constructed the plasmid 2. The two plasmids were co-expressed and the FCGRT/B2M heterodimer was purified.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,169 Da
NCBI Official Full Name
IgG receptor FcRn large subunit p51
NCBI Official Synonym Full Names
Fc fragment of IgG receptor and transporter
NCBI Official Symbol
Fcgrt
NCBI Official Synonym Symbols
FcRn
NCBI Protein Information
IgG receptor FcRn large subunit p51
UniProt Protein Name
IgG receptor FcRn large subunit p51
Protein Family
UniProt Gene Name
Fcgrt
UniProt Synonym Gene Names
Fcrn; FcRn
NCBI Description
binds and transports maternal immunoglobulin gamma from milk; plays a role in providing maternal immunity to neonates [RGD, Feb 2006]
Uniprot Description
FCGRT: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily.
Protein type: Immunoglobulin superfamily; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1q22
Cellular Component: plasma membrane
Molecular Function: antigen binding; beta-2-microglobulin binding; IgG binding; IgG receptor activity; peptide antigen binding
Biological Process: antigen processing and presentation; humoral immune response
Research Articles on FCGRT
Similar Products
Product Notes
The FCGRT fcgrt (Catalog #AAA2547253) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant heterodimer of rat FCGRT & B2M comprises 386 (287+99) amino acids and has a calculated molecular mass of 44 (32.4+ 11.6) KDa. The apparent molecular mass of rat FCGRT & B2M heterodimer is approximately 35 & 12 KDa respectively in SDS-PAGE. Researchers should empirically determine the suitability of the FCGRT fcgrt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCGRT & B2M Heterodimer, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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