Rabbit anti-Human B7-H1/PD-L1 Monoclonal Antibody | anti-B7-H1/PD-L1 antibody
Rabbit anti Human B7-H1/PD-L1 Monoclonal Antibody
Reactivity
Human
Applications
ELISA
Purity
Affinity Purification
Synonyms
B7-H1/PD-L1 ; Monoclonal Antibody; Rabbit anti Human B7-H1/PD-L1 Monoclonal Antibody; Anti-B7-H Antibody; Anti-B7-H1 Antibody; Anti-B7H1 Antibody; Anti-PD-L1 Antibody; Anti-PDCD1L1 Antibody; Anti-PDCD1LG1 Antibody; Anti-PDL1 Antibody; anti-B7-H1/PD-L1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Applicable Applications for anti-B7-H1/PD-L1 antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000 - 1:10000
Immunogen
Recombinant Human B7-H1 protein
Buffer
0.2 mum filtered solution in PBS
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at 20°C. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-B7-H1/PD-L1 antibody
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1 (PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 family expressed on activated lymphoid cells. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
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Product Notes
The B7-H1/PD-L1 (Catalog #AAA2543836) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human B7-H1/PD-L1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's B7-H1/PD-L1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000 - 1:10000. Researchers should empirically determine the suitability of the B7-H1/PD-L1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "B7-H1/PD-L1 , Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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