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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer using USP47 Polyclonal Antibody at dilution of 1/20)

Rabbit anti-Human, Mouse USP47 Polyclonal Antibody | anti-USP47 antibody

USP47 Polyclonal Antibody

Gene Names
USP47; TRFP
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
USP47; Polyclonal Antibody; USP47 Polyclonal Antibody; TRFP; anti-USP47 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Concentration
2.2mg/ml (varies by lot)
Sequence Length
1375
Applicable Applications for anti-USP47 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-2000
IHC: 1:25-100
WB: 1:200-1000
Immunogen
Fusion protein of human USP47
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human breast cancer using USP47 Polyclonal Antibody at dilution of 1/20)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer using USP47 Polyclonal Antibody at dilution of 1/20)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human prostate cancer using USP47 Polyclonal Antibody at dilution of 1/20)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human prostate cancer using USP47 Polyclonal Antibody at dilution of 1/20)
Related Product Information for anti-USP47 antibody
Ubiquitin carboxyl-terminal hydrolase 47 is an enzyme that in humans is encoded by the USP47 gene. Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulates CDC25A expression at a transcriptional level.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
157 kDa
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 47 isoform c
NCBI Official Synonym Full Names
ubiquitin specific peptidase 47
NCBI Official Symbol
USP47
NCBI Official Synonym Symbols
TRFP
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 47
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 47
UniProt Gene Name
USP47
UniProt Entry Name
UBP47_HUMAN

Uniprot Description

USP47: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulates CDC25A expression at a transcriptional level. Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding; EC 3.4.19.12; Motility/polarity/chemotaxis; Protease; Ubiquitin conjugating system; Ubiquitin-specific protease

Chromosomal Location of Human Ortholog: 11p15.3

Cellular Component: cytoplasm; nucleus; SCF ubiquitin ligase complex

Molecular Function: protein binding; ubiquitin-specific protease activity

Biological Process: base-excision repair; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of transcription, DNA-dependent; positive regulation of cell growth; response to DNA damage stimulus; response to drug

Research Articles on USP47

Similar Products

Product Notes

The USP47 usp47 (Catalog #AAA2542645) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP47 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's USP47 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-2000 IHC: 1:25-100 WB: 1:200-1000. Researchers should empirically determine the suitability of the USP47 usp47 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP47, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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