Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat lung using IL10 Polyclonal Antibody at dilution of 1:50)
Rabbit anti-Rat, Mouse IL10 Polyclonal Antibody | anti-IL10 antibody
IL10 Polyclonal Antibody
Gene Names
IL10; CSIF; TGIF; GVHDS; IL-10; IL10A
Reactivity
Rat, Mouse
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
IL10; Polyclonal Antibody; IL10 Polyclonal Antibody; CSIF; IL-10; IL10A; interleukin 10; TGIF; anti-IL10 antibody
Host
Rabbit
Reactivity
Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Concentration
3mg/ml (varies by lot)
Sequence Length
178
Applicable Applications for anti-IL10 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:100
Immunogen
Recombinant Mouse Interleukin-10 protein
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7888
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat lung using IL10 Polyclonal Antibody at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat lung using IL10 Polyclonal Antibody at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Mouse brain using IL10 Polyclonal Antibody at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Mouse brain using IL10 Polyclonal Antibody at dilution of 1:50)
Related Product Information for anti-IL10 antibody
Interleukin (IL)-10 is an anti-inflammatory cytokine, produced by T helper (Th) cells, macrophages, monocytes, and B cells, that plays a crucial role in preventing inflammatory and autoimmune pathologies. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kappaB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL-10, along with its receptors, describes an important role in pathogenesis of various diseases, including infectious, inflammatory, autoimmune diseases. IL-10 mutations are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Product Categories/Family for anti-IL10 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
20,493 Da
NCBI Official Full Name
IL10, partial
NCBI Official Synonym Full Names
interleukin 10
NCBI Official Symbol
IL10
NCBI Official Synonym Symbols
CSIF; TGIF; GVHDS; IL-10; IL10A
NCBI Protein Information
interleukin-10
UniProt Protein Name
IL10 protein
Protein Family
UniProt Gene Name
IL10
UniProt Entry Name
Q6FGS9_HUMAN
NCBI Description
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Research Articles on IL10
Similar Products
Product Notes
The IL10 il10 (Catalog #AAA2541767) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL10 Polyclonal Antibody reacts with Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IL10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:100. Researchers should empirically determine the suitability of the IL10 il10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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