Human PRB2 (Basic Salivary Proline Rich Protein 2) CLIA Kit | PRB2 clia kit

Human PRB2 (Basic Salivary Proline Rich Protein 2) CLIA Kit

Cat. Num. AAA2532612

• Gene Names: PRB2; Ps; cP7; IB-9; PRPPRB1
• Reactivity: Human
• Synonyms: PRB2 (Basic Salivary Proline Rich Protein 2); Human PRB2 (Basic Salivary Proline Rich Protein 2) CLIA Kit; PRB2 clia kit

• Reactivity: Human
• Specificity: This kit recognizes natural and recombinant PRB2. No significant cross-reactivity or interference between PRB2 and analogues was observed.
• Sequence Length: 416

• Assay Type: Sandwich
• Detection Range: 15.625-1000pg/mL
• Sensitivity: Min: 9.375pg/mL; Max: 1000pg/mL

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for PRB2 clia kit

Intended Uses: This CLIA kit applies to the in vitro quantitative determination of PRB2 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to PRB2. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PRB2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PRB2, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of PRB2. You can calculate the concentration of PRB2 in the samples by comparing the RLU value of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 209571537
• NCBI GeneID: 653247
• NCBI Accession #: NP_006239.3
• NCBI GenBank Nucleotide #: NM_006248.3
• Molecular Weight: 40,799 Da
• NCBI Official Full Name: basic salivary proline-rich protein 2
• NCBI Official Synonym Full Names: proline-rich protein BstNI subfamily 2
• NCBI Official Symbol: PRB2
• NCBI Official Synonym Symbols: Ps; cP7; IB-9; PRPPRB1
• NCBI Protein Information: basic salivary proline-rich protein 2
• UniProt Protein Name: Basic salivary proline-rich protein 2
• Protein Family: Basic salivary proline-rich protein
• UniProt Gene Name: PRB2
• UniProt Synonym Gene Names: Salivary proline-rich protein
• UniProt Entry Name: PRB2_HUMAN

Uniprot Description

PRB2: N- and O-glycosylated. In head and neck cancer patients, O-glycosylated with glucosylgalactosyl carbohydrate moiety. This modification would require prior hydroxylation on the lysine residue. Proteolytically cleaved at the tripeptide Xaa-Pro-Gln, where Xaa in the P3 position is mostly lysine. The endoprotease may be of microbial origin. Pyroglutamate formation occurs on terminal Gln residues of cleaved peptides. Pyroglutamate formation found on at least Gln-398 and Gln-400.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12p13.2

Cellular Component: extracellular region