Typical Testing Data/Standard Curve (for reference only)
Human CTSV (Cathepsin V) CLIA Kit | CTSV clia kit
Human CTSV (Cathepsin V) CLIA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to CTSV. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for CTSV and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain CTSV, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of CTSV. You can calculate the concentration of CTSV in the samples by comparing the RLU value of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]
Uniprot Description
CTSL2: Cysteine protease. May have an important role in corneal physiology. Belongs to the peptidase C1 family.
Protein type: EC 3.4.22.15; Secreted, signal peptide; Protease; Secreted
Chromosomal Location of Human Ortholog: 9q22.2
Cellular Component: extracellular space; lysosomal lumen; neuron projection; microvillus; lysosome; apical part of cell; nucleolus; extracellular region; perikaryon; secretory granule; external side of plasma membrane
Molecular Function: protein binding; histone binding; cysteine-type endopeptidase activity; protein complex binding; aminopeptidase activity; kininogen binding; cysteine-type carboxypeptidase activity; peptide binding; cysteine-type peptidase activity
Biological Process: extracellular matrix organization and biogenesis; hair follicle morphogenesis; response to glucocorticoid stimulus; Sertoli cell differentiation; antigen processing and presentation of exogenous peptide antigen via MHC class II; multicellular organismal aging; decidualization; cellular response to starvation; extracellular matrix disassembly; protein autoprocessing; proteolysis involved in cellular protein catabolic process; autophagic cell death; response to glucose stimulus; spermatogenesis; nerve development
Research Articles on CTSV
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Product Notes
The Human CTSV ctsv (Catalog #AAA2532544) is a CLIA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2532544 CLIA Kit recognizes Human CTSV. It is sometimes possible for the material contained within the vial of "CTSV (Cathepsin V), CLIA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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