Rabbit KCNQ1 Polyclonal Antibody | anti-KCNQ1 antibody
KCNQ1 Antibody
NCBI and Uniprot Product Information
Uniprot Description
Kv7.1: a voltage-gated potassium channel protein required for the repolarization phase of the cardiac action potential. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea. Abundantly expressed in heart, pancreas, prostate, kidney, small intestine and peripheral blood leukocytes. Less abundant in placenta, lung, spleen, colon, thymus, testis and ovaries. Three alternatively spliced isoforms have been described.
Protein type: Membrane protein, multi-pass; Channel, potassium; Membrane protein, integral
Cellular Component: voltage-gated potassium channel complex; zymogen granule membrane; cytoplasmic vesicle membrane; lysosome; integral to plasma membrane; basolateral plasma membrane; early endosome; integral to membrane; membrane; late endosome; plasma membrane; cytoplasmic vesicle; sarcolemma
Molecular Function: calmodulin binding; voltage-gated potassium channel activity; protein homodimerization activity; potassium channel activity; outward rectifier potassium channel activity; delayed rectifier potassium channel activity; ion channel activity; voltage-gated ion channel activity; protein phosphatase 1 binding
Biological Process: regulation of membrane potential; genetic imprinting; transport; positive regulation of heart rate; ion transport; gene silencing; transmembrane transport; potassium ion transport; negative regulation of insulin secretion; cardiac muscle contraction
Research Articles on KCNQ1
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Product Notes
The KCNQ1 kcnq1 (Catalog #AAA2528732) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNQ1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KCNQ1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the KCNQ1 kcnq1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNQ1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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