Western Blot (WB)
(Western blot analysis of extracts of NCI-H460 cell lines, using PLCB1 antibody.)
Rabbit PLCB1 Polyclonal Antibody | anti-PLCB1 antibody
PLCB1 Antibody
Western Blot (WB)
(Western blot analysis of extracts of NCI-H460 cell lines, using PLCB1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of NCI-H460 cell lines, using PLCB1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human breast cancer using PLCB1 antibody at dilution of 1:200 (400x lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human breast cancer using PLCB1 antibody at dilution of 1:200 (400x lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat lung using PLCB1 antibody at dilution of 1:200 (400x lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat lung using PLCB1 antibody at dilution of 1:200 (400x lens).)
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cell using PLCB1 antibody. Blue: DAPI for nuclear staining.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cell using PLCB1 antibody. Blue: DAPI for nuclear staining.)
NCBI and Uniprot Product Information
Uniprot Description
PLCB1: an enzyme that catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. Binds to calmodulin. Uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variant isoforms have been described.
Protein type: Carbohydrate Metabolism - inositol phosphate; Phospholipase; EC 3.1.4.11
Cellular Component: membrane; nuclear chromatin; cytoplasm; nuclear speck; cytosol; nucleus; myelin sheath
Molecular Function: calmodulin binding; signal transducer activity; phosphatidylinositol-4,5-bisphosphate binding; protein binding; protein homodimerization activity; enzyme binding; phosphoric diester hydrolase activity; hydrolase activity; calcium ion binding; phosphoinositide phospholipase C activity; GTPase activator activity; lamin binding
Biological Process: fat cell differentiation; response to peptide hormone stimulus; macrophage differentiation; positive regulation of interleukin-12 production; regulation of cell cycle; positive regulation of transcription, DNA-dependent; positive regulation of JNK cascade; signal transduction; erythrocyte differentiation; G2/M transition of mitotic cell cycle; cell adhesion; positive regulation of developmental growth; acetylcholine receptor signaling, muscarinic pathway; glutamate signaling pathway; oocyte maturation; memory; positive regulation of myoblast differentiation; positive regulation of embryonic development; insulin-like growth factor receptor signaling pathway; insulin receptor signaling pathway; brain development; cerebral cortex development; positive regulation of sodium:hydrogen antiporter activity; lipid metabolic process; negative regulation of transcription, DNA-dependent; mRNA processing; regulation of G-protein coupled receptor protein signaling pathway; lipid catabolic process; positive regulation of GTPase activity
Research Articles on PLCB1
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Product Notes
The PLCB1 plcb1 (Catalog #AAA2524079) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLCB1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLCB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the PLCB1 plcb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLCB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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