Immunohistochemistry (IHC)
(Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Goat Kinesin Heavy Chain / KIF5B Polyclonal Antibody | anti-KIF5B antibody
Goat Polyclonal to Human Kinesin Heavy Chain / KIF5B
Gene Names
KIF5B; KNS; KINH; KNS1; UKHC; HEL-S-61
Reactivity
Gibbon, Bovine, Dog, Gorilla, Human, Monkey, Pig, RabbitPredicted Reactivity: Horse (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
Kinesin Heavy Chain / KIF5B; Polyclonal Antibody; Goat Polyclonal to Human Kinesin Heavy Chain / KIF5B; Anti-Kinesin Heavy Chain / KIF5B Antibody (C-Terminus) IHC-plus; KIF5B; Kinesin 1 (110-120kD); KINH; KNS; Kinesin family member 5B; Kinesin heavy chain; KNS1; UKHC; Kinesin-1 heavy chain; Ubiquitous kinesin heavy chain; Human Kinesin Heavy Chain; anti-KIF5B antibody
Host
Goat
Reactivity
Gibbon, Bovine, Dog, Gorilla, Human, Monkey, Pig, Rabbit
Predicted Reactivity: Horse (at least 90% immunogen sequence identity)
Predicted Reactivity: Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human KIF5B.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
963
Applicable Applications for anti-KIF5B antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:32000), IHC-P (2.5 ug/ml), WB (0.2 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Synthetic peptide C-QPVAVRGGGGKQV from the C-terminus of human KIF5B (NP_004512.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bovine, Rabbit, Pig (100%); Elephant, Panda, Horse (92%); Turkey, Platypus (85%).
Immunogen Type
Synthetic peptide
Immunogen
Kinesin Heavy Chain / KIF5B antibody was raised against synthetic peptide C-QPVAVRGGGGKQV from the C-terminus of human KIF5B (NP_004512.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bovine, Rabbit, Pig (100%); Elephant, Panda, Horse (92%); Turkey, Platypus (85%).
Antigen Modification
C-Terminus
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Immunohistochemistry (IHC)
(Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
109,685 Da
NCBI Official Full Name
kinesin-1 heavy chain
NCBI Official Synonym Full Names
kinesin family member 5B
NCBI Official Symbol
KIF5B
NCBI Official Synonym Symbols
KNS; KINH; KNS1; UKHC; HEL-S-61
NCBI Protein Information
kinesin-1 heavy chain; kinesin heavy chain; kinesin 1 (110-120kD); ubiquitous kinesin heavy chain; conventional kinesin heavy chain; epididymis secretory protein Li 61
UniProt Protein Name
Kinesin-1 heavy chain
Protein Family
UniProt Gene Name
KIF5B
UniProt Synonym Gene Names
KNS; KNS1; UKHC
UniProt Entry Name
KINH_HUMAN
Uniprot Description
KIF5B: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Belongs to the kinesin-like protein family. Kinesin subfamily.
Protein type: Motor; Microtubule-binding
Chromosomal Location of Human Ortholog: 10p11.22
Cellular Component: ciliary rootlet; microtubule; kinesin complex; neuron projection; membrane; perinuclear region of cytoplasm; endocytic vesicle; cytoplasm; microtubule organizing center; vesicle
Molecular Function: protein binding; plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; microtubule motor activity; ATP binding
Biological Process: axon guidance; regulation of membrane potential; cellular protein metabolic process; positive regulation of potassium ion transport; vesicle transport along microtubule; positive regulation of synaptic transmission, GABAergic; cytoplasm organization and biogenesis; cytoskeleton-dependent intracellular transport; microtubule-based movement
Research Articles on KIF5B
Similar Products
Product Notes
The KIF5B kif5b (Catalog #AAA242067) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human Kinesin Heavy Chain / KIF5B reacts with Gibbon, Bovine, Dog, Gorilla, Human, Monkey, Pig, Rabbit Predicted Reactivity: Horse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's Kinesin Heavy Chain / KIF5B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:32000), IHC-P (2.5 ug/ml), WB (0.2 - 1 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the KIF5B kif5b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kinesin Heavy Chain / KIF5B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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