Mouse anti-Human TES/Testin Monoclonal Antibody | anti-TES antibody

Anti-TES/Testin Antibody (clone 1G11-B7)

Cat. Num. AAA2400654

• Gene Names: TES; TESS; TESS-2
• Reactivity: Human
• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Purified from ascites by Protein A
• Synonyms: TES/Testin; Monoclonal Antibody; Anti-TES/Testin Antibody (clone 1G11-B7); Mouse Monoclonal (IgG1; k) to Human TES/Testin; TES; DKFZP586B2022; TESS-2; TESS; Testin; anti-TES antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1, k
• Clone Number: 1G11-B7
• Specificity: Human TES
• Purity/Purification: Purified from ascites by Protein A
• Form/Format: PBS, pH 7.4.
• Sequence Length: 421

• Applicable Applications for anti-TES antibody: ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IF: 10 ug/ml; IHC-P: 3-5 ug/ml; WB: 1:500-1:1000
• Immunogen: TES (AAH01451, 1 a.a. ~ 422 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C or lower.; Aliquot to avoid repeated freezing and thawing.

Immunohistochemistry (IHC)

(Anti-TES/Testin antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of monoclonal antibody to TES on HeLa cell. [antibody concentration 10 ug/ml])

Western Blot (WB)

(Antibody Western blot of TES expression in K-562.)

Related Product Information for anti-TES antibody

Cancer-associated chromosomal changes often involve regions containingfragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, atestosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein -protein interactions between transcription factors, cytoskeletal proteins and signaling proteins.

NCBI and Uniprot Product Information

• NCBI GI #: 7661666
• NCBI GeneID: 26136
• NCBI Accession #: NP_056456.1
• NCBI GenBank Nucleotide #: NM_015641.3
• UniProt Accession #: Q9UGI8; Q9GZQ1; Q9HAJ9; A4D0U6
• Molecular Weight: 46,910 Da
• NCBI Official Full Name: testin isoform 1
• NCBI Official Synonym Full Names: testin LIM domain protein
• NCBI Official Symbol: TES
• NCBI Official Synonym Symbols: TESS; TESS-2
• NCBI Protein Information: testin
• UniProt Protein Name: Testin
• Protein Family: Testin
• UniProt Gene Name: TES

NCBI Description

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011]

Uniprot Description

Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.