Western Blot (WB)
(Western blot analysis of Jurkat cell lysate probed with Rabbit anti PDPK1 antibody)
Rabbit anti-Human PDKP1 Polyclonal Antibody | anti-PDKP1 antibody
RABBIT ANTI PDKP1
Immunohistochemistry-Paraffin: 15; 25 ug/ml
Western Blot: 0.5; 4.0 ug/ml
Shelf Life: 12 months from date of despatch
Western Blot (WB)
(Western blot analysis of Jurkat cell lysate probed with Rabbit anti PDPK1 antibody)
Western Blot (WB)
(Western blot analysis of Jurkat cell lysate probed with Rabbit anti PDPK1 antibody)
NCBI and Uniprot Product Information
Uniprot Description
PDK1: an AGC kinase of the PKB family that contains a PH domain. Involved in a wide variety of processes including cell proliferation, differentiation and apoptosis. Autophosphorylation in the activation loop is necessary for activity. Phosphorylates and activates kinases including Akt, PKC isozymes, p70 S6K and RSK. Three alternatively-spliced isoforms have been described.
Protein type: Nuclear receptor co-regulator; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Kinase, protein; AGC group; PKB family
Cellular Component: cell junction; cell projection; cytoplasm; cytoplasmic membrane-bound vesicle; cytosol; membrane; nucleus; perikaryon; plasma membrane
Molecular Function: 3-phosphoinositide-dependent protein kinase activity; ATP binding; insulin receptor binding; kinase activity; nucleotide binding; phospholipase activator activity; phospholipase binding; protein binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; transferase activity
Biological Process: activation of protein kinase B; calcium-mediated signaling; cell migration; cellular response to insulin stimulus; epidermal growth factor receptor signaling pathway; focal adhesion formation; hyperosmotic response; negative regulation of neuron apoptosis; negative regulation of protein kinase activity; negative regulation of toll-like receptor signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; phosphorylation; positive regulation of release of sequestered calcium ion into cytosol; protein amino acid phosphorylation; regulation of I-kappaB kinase/NF-kappaB cascade; regulation of mast cell degranulation; regulation of transcription, DNA-dependent; signal transduction; transcription, DNA-dependent
Research Articles on PDKP1
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Product Notes
The PDKP1 pdpk1 (Catalog #AAA224875) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI PDKP1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDKP1 can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). Immunoprecipitation: 10; 20 ug/ml Immunohistochemistry-Paraffin: 15; 25 ug/ml Western Blot: 0.5; 4.0 ug/ml. Researchers should empirically determine the suitability of the PDKP1 pdpk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDKP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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