Testing Data #1
(Western blot analysis of whole cell lysate from mouse 3T3 cells probed with Rabbit anti RIP3 (MBS223753) in the absence (A) or presence (B) of blocking peptide)
Rabbit anti-Rat RIP3 Polyclonal Antibody | anti-RIP3 antibody
RABBIT ANTI RIP3
Purified IgG - liquid
Immunohistology - Paraffin: Maximum Dilution: 5ug/ml; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Western Blotting: Minimum Dilution: 0.5; Maximum Dilution: 1.0ug/ml
Histology Positive Control Tissue
Shelf Life: 18 months from date of despatch.
Testing Data #1
(Western blot analysis of whole cell lysate from mouse 3T3 cells probed with Rabbit anti RIP3 (MBS223753) in the absence (A) or presence (B) of blocking peptide)
Testing Data #1
(Western blot analysis of whole cell lysate from mouse 3T3 cells probed with Rabbit anti RIP3 (MBS223753) in the absence (A) or presence (B) of blocking peptide)
Testing Data #2
(Immunohistochemical staining of rat kidney with Rabbit anti RIP3 (MBS223753))
Testing Data #2
(Immunohistochemical staining of rat kidney with Rabbit anti RIP3 (MBS223753))
NCBI and Uniprot Product Information
Uniprot Description
RIPK3: Promotes apoptosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Binds TRAF2 and RIPK1 and is recruited to the TNFR-1 signaling complex. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, TKL; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); TKL group; RIPK family
Cellular Component: membrane; mitochondrion; cytoplasm; plasma membrane; intracellular; cytosol
Molecular Function: transferase activity; NF-kappaB-inducing kinase activity; protein serine/threonine kinase activity; identical protein binding; protein binding; transferase activity, transferring phosphorus-containing groups; protein complex binding; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: spleen development; I-kappaB kinase/NF-kappaB cascade; regulation of activated T cell proliferation; thymus development; viral reproduction; protein heterooligomerization; protein amino acid autophosphorylation; programmed cell death; T cell differentiation in the thymus; positive regulation of transferase activity; protein amino acid phosphorylation; lymph node development; activation of NF-kappaB transcription factor; regulation of T cell mediated cytotoxicity; regulation of adaptive immune response; regulation of interferon-gamma production; activation of protein kinase activity; T cell homeostasis; positive regulation of ligase activity; phosphorylation; protein homooligomerization; positive regulation of oxidoreductase activity
Research Articles on RIP3
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Product Notes
The RIP3 ripk3 (Catalog #AAA223753) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI RIP3 reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RIP3 can be used in a range of immunoassay formats including, but not limited to, Immunohistology Paraffin*, Western Blot (WB). Western Blot: This item detects a band of approximately 56 kDa in Mouse 3T3 whole cell lysate Immunohistology - Paraffin: Maximum Dilution: 5ug/ml; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Western Blotting: Minimum Dilution: 0.5; Maximum Dilution: 1.0ug/ml. Researchers should empirically determine the suitability of the RIP3 ripk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RIP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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