Rabbit DYNORPHIN B Polyclonal Antibody | anti-PDYN antibody
RABBIT ANTI DYNORPHIN B (aa1-13)
Reactivity
Bovine (Expected from Sequence), Chimpanzee (Expected from Sequence), Dog (Expected from Sequence), Gorilla (Expected from Sequence), Guinea Pig, Hamster, Horse (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence), Mous
Applications
Immunohistochemistry, immunoassay, Radioimmunoassay
Synonyms
DYNORPHIN B; Polyclonal Antibody; RABBIT ANTI DYNORPHIN B (aa1-13); anti-PDYN antibody
Host
Rabbit
Reactivity
Bovine (Expected from Sequence), Chimpanzee (Expected from Sequence), Dog (Expected from Sequence), Gorilla (Expected from Sequence), Guinea Pig, Hamster, Horse (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence), Mous
Clonality
Polyclonal
Isotype
IgG
Form/Format
Serum
Serum - liquid
Serum - liquid
Sequence Length
256
Applicable Applications for anti-PDYN antibody
Immunohistology Frozen, Radioimmunoassays (RIA)
Application Notes
Immunohistology - Frozen: Minimum Dilution: 1/250; Maximum Dilution: 1/2500;
Radioimmunoassays: Maximum Dilution: 1/5000
Radioimmunoassays: Maximum Dilution: 1/5000
Perservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
1% Bovine Serum Albumin
Buffer Solution
Phosphate buffered saline
Antiserum Preparation
Antisera to Dynorphin B (1-13) were raised by repeated immunisation of rabbits with highly purified antigen.
Target Species
Pig
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-PDYN antibody
Rabbit anti Dynorphin B antibody recognizes dynorphin B, an endogenous opioid peptide, also known as rimorphin with the peptide sequence Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr, derived from the sequential cleavage of pro-enkephalin B to form leumorphin which is, in turn cleaved to form dynorphin B (Devi et al. 1985). The cleavage of the dynorphin precursors to form the dynorphin neuropeptides is largely controlled by the serine protease cathepsin L which co-localizes with dynorphins in secretory vesicles of brain cortical neurons(Funkelstein et al. 2010) and prohormone convertase 2, a member of the furin, peptidate S8 family (Schwarzer 2009). Dynorphin b sequence is well conserved among mammal, avian (Youngren et al. 1993) and reptilian (Goldsmith et al. 1992) species. Rabbit anti Dynorphin b antibody is expected to have a wide species cross reactivity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,617 Da
NCBI Official Full Name
proenkephalin-B preproprotein
NCBI Official Symbol
PDYN
NCBI Protein Information
proenkephalin-B; beta-neoendorphin-dynorphin; preprodynorphin
UniProt Protein Name
Proenkephalin-B
Protein Family
UniProt Gene Name
PDYN
UniProt Synonym Gene Names
Big Dyn; Dyn-A17; Dynorphin A; Dyn-B
UniProt Entry Name
PDYN_PIG
Uniprot Description
Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress ().
Research Articles on PDYN
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Product Notes
The PDYN pdyn (Catalog #AAA222378) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI DYNORPHIN B (aa1-13) reacts with Bovine (Expected from Sequence), Chimpanzee (Expected from Sequence), Dog (Expected from Sequence), Gorilla (Expected from Sequence), Guinea Pig, Hamster, Horse (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence), Mous and may cross-react with other species as described in the data sheet. AAA Biotech's DYNORPHIN B can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Radioimmunoassays (RIA). Immunohistology - Frozen: Minimum Dilution: 1/250; Maximum Dilution: 1/2500; Radioimmunoassays: Maximum Dilution: 1/5000. Researchers should empirically determine the suitability of the PDYN pdyn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYNORPHIN B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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