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Rabbit IL-1 ALPHA Polyclonal Antibody | anti-Il1a antibody

RABBIT ANTI MOUSE INTERLEUKIN-1 ALPHA

Gene Names
Il1a; Il-1a
Applications
ELISA, Functional Assay, Western Blot
Synonyms
IL-1 ALPHA; Polyclonal Antibody; RABBIT ANTI MOUSE INTERLEUKIN-1 ALPHA; anti-Il1a antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Purified
Purified IgG - lyophilised
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
270
Applicable Applications for anti-Il1a antibody
ELISA (EIA), Functional Assays (FN), Western Blot (WB)
Application Notes
ELISA: Maximum Dilution: 0.5ug/ml;
Functional Assays: Minimum Dilution: 0.03ug/ml; Maximum Dilution: 0.05ug/ml;
Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 0.2ug/ml
Reconstitution
Reconstitute with 0.1 ml distilled water
Immunogen
Recombinant mouse IL-1 alpha
Buffer Solution
Antiserum Preparation
Antisera to mouse IL-1 alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Target Species
Mouse
Preparation and Storage
Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. For long term storage, the addition of 0. 09% sodium azide is recommended. N. B. For functional studies do not add azide.
Shelf Life: 12 months from date of reconstitution.
Related Product Information for anti-Il1a antibody
Rabbit anti Mouse Interleukin-1 alpha antibody recognizes mouse interleukin-1 alpha (IL-1 alpha). Interleukin-1 alpha is a potent immuno-modulator, which mediates a wide range of immune and inflammatory responses.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,023 Da
NCBI Official Full Name
interleukin-1 alpha
NCBI Official Synonym Full Names
interleukin 1 alpha
NCBI Official Symbol
Il1a
NCBI Official Synonym Symbols
Il-1a
NCBI Protein Information
interleukin-1 alpha; IL-1 alpha
UniProt Protein Name
Interleukin-1 alpha
Protein Family
UniProt Gene Name
Il1a
UniProt Synonym Gene Names
IL-1 alpha
UniProt Entry Name
IL1A_MOUSE

Uniprot Description

IL1A: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Belongs to the IL-1 family.

Protein type: Motility/polarity/chemotaxis; Cytokine

Cellular Component: extracellular space; cell surface; plasma membrane; extracellular region; cytosol

Molecular Function: interleukin-1 receptor binding; copper ion binding; cytokine activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of mitosis; positive regulation of interleukin-2 biosynthetic process; cytokine and chemokine mediated signaling pathway; germ cell programmed cell death; positive regulation of JNK cascade; positive regulation of interleukin-6 production; fever; positive regulation of stress-activated MAPK cascade; negative regulation of cell proliferation; connective tissue replacement during inflammatory response; positive regulation of angiogenesis; response to copper ion; keratinization; positive regulation of cell division; positive regulation of prostaglandin secretion; immune response; positive regulation of transcription from RNA polymerase II promoter; regulation of sensory perception of pain; inflammatory response; positive regulation of cytokine secretion

Research Articles on Il1a

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Product Notes

The Il1a il1a (Catalog #AAA221261) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IL-1 ALPHA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Functional Assays (FN), Western Blot (WB). ELISA: Maximum Dilution: 0.5ug/ml; Functional Assays: Minimum Dilution: 0.03ug/ml; Maximum Dilution: 0.05ug/ml; Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 0.2ug/ml. Researchers should empirically determine the suitability of the Il1a il1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-1 ALPHA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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