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Rat CD1d Monoclonal Antibody | anti-CD1d antibody

RAT ANTI MOUSE CD1d

Gene Names
Cd1d1; Cd1a; Cd1d; CD1.1; Ly-38; AI747460
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay, Immunoprecipitation
Synonyms
CD1d; Monoclonal Antibody; RAT ANTI MOUSE CD1d; anti-CD1d antibody
Ordering
For Research Use Only!
Host
Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
1B1
Specificity
This item recognises mouse CD1d, a glycoprotein expressed on cortical thymocytes, certain T-cell leukaemias and various other antigen presenting cells. CD1d binds self and non-self glycolipids and presents them to T-cell receptors on natural killer cells. When activated, natural killer cells produce Th1 and Th2 cytokines.
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 0.5mg/ml (varies by lot)
Sequence Length
336
Applicable Applications for anti-CD1d antibody
Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP)
Application Notes
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/20
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Immunogen
Mouse CD1d cDNA-transfected RMA-S mouse T lymphoma.
Buffer Solution
Target Species
Mouse
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-CD1d antibody
MBS219537 recognises mouse CD1d, a glycoprotein expressed on cortical thymocytes, certain T-cell leukaemias and various other antigen presenting cells. CD1d binds self and non-self glycolipids and presents them to T-cell receptors on natural killer cells. When activated, natural killer cells produce Th1 and Th2 cytokines.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,554 Da
NCBI Official Full Name
antigen-presenting glycoprotein CD1d1
NCBI Official Synonym Full Names
CD1d1 antigen
NCBI Official Symbol
Cd1d1
NCBI Official Synonym Symbols
Cd1a; Cd1d; CD1.1; Ly-38; AI747460
NCBI Protein Information
antigen-presenting glycoprotein CD1d1; T-cell surface glycoprotein CD1d1
UniProt Protein Name
Antigen-presenting glycoprotein CD1d1
UniProt Gene Name
Cd1d1
UniProt Synonym Gene Names
Cd1.1
UniProt Entry Name
CD1D1_MOUSE

Uniprot Description

CD1D: Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.

Protein type: Lipid-binding; Apoptosis; Membrane protein, integral; Cell surface

Cellular Component: cell surface; membrane; lysosome; early endosome; late endosome; cytoplasm; plasma membrane; integral to membrane; endosome; external side of plasma membrane

Molecular Function: protein binding; histone binding; beta-2-microglobulin binding; exogenous lipid antigen binding; T cell receptor binding; lipid antigen binding; cell adhesion molecule binding; endogenous lipid antigen binding

Biological Process: antigen processing and presentation, endogenous lipid antigen via MHC class Ib; regulation of immune response; positive regulation of NK T cell activation; positive regulation of T cell mediated cytotoxicity; immune system process; positive regulation of interleukin-2 biosynthetic process; antigen processing and presentation; positive regulation of interleukin-4 biosynthetic process; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; innate immune response; positive regulation of NK T cell differentiation; immune response; positive regulation of T cell proliferation; positive regulation of macrophage activation; positive thymic T cell selection; positive regulation of interferon-gamma biosynthetic process

Research Articles on CD1d

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Product Notes

The CD1d cd1d1 (Catalog #AAA219537) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD1d can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP). Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/20. Researchers should empirically determine the suitability of the CD1d cd1d1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD1d, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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